@article{fdi:010073038, title = {{E}valuation of malaria urban risk using an immuno-epidemiological biomarker of human exposure to anopheles bites}, author = {{T}raor{\'e}, {D}ipomin and {S}agna, {A}. {B}. and {A}dja, {A}. {M}. and {Z}oh, {D}. {D}. and {L}ingue, {K}. {N}. and {C}oulibaly, {I}. and {T}chiekoi, {B}. {N}. and {A}ssi, {S}. {B}. and {P}oinsignon, {A}nne and {D}agnogo, {M}. and {R}emou{\'e}, {F}ranck}, editor = {}, language = {{ENG}}, abstract = {{U}rban malaria is an underestimated serious health concern in {A}frican countries. {T}his study aimed to evaluate the risk of malaria transmission in an urban area by evaluating the level of human exposure to {A}nopheles bites using an {A}nopheles salivary biomarker (gambiae {S}alivary {G}land {P}rotein-6 peptide 1 [g{SG}6-{P}1] peptide). {T}wo multidisciplinary cross-sectional studies were undertaken in five sites of {B}ouake city (three urban districts and two surrounding villages, used as control; {C}ote d'{I}voire) during the rainy season and the dry season. {B}lood samples were obtained from children 6 months to 14 years of age for immunological tests. {T}he level of anti-g{SG}6-{P}1 immunoglobulin {G} ({I}g{G}) antibodies was significantly higher in the rainy season than the dry season in both urban and rural sites ({P} < 0.0001). {I}nterestingly, children with the highest anti-g{SG}6-{P}1 {I}g{G} responses in the rainy season were infected by {P}lasmodium falciparum. {S}urprisingly, no difference of anti-g{SG}6-{P}1 {I}g{G} level was observed between urban and rural areas, for either season. {T}he current data suggest that children in the urban city of {B}ouake ' could be as highly exposed to {A}nopheles bites as children living in surrounding villages. {T}he immunological biomarker of human exposure to {A}nopheles bites may be used to accurately assess the potential risk of malaria transmission in {A}frican urban settings.}, keywords = {}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {98}, numero = {5}, pages = {1353--1359}, ISSN = {0002-9637}, year = {2018}, DOI = {10.4269/ajtmh.17-0231}, URL = {https://www.documentation.ird.fr/hor/fdi:010073038}, }