@article{fdi:010072810, title = {{S}ex-specific association between neighborhood characteristics and dementia : the {T}hree-{C}ity cohort}, author = {{L}etellier, {N}. and {G}utierrez, {L}. {A}. and {C}arriere, {I}. and {G}abelle, {A}. and {D}artigues, {J}. {F}. and {D}ufouil, {C}. and {H}elmer, {C}. and {C}adot, {E}mmanuelle and {B}err, {C}.}, editor = {}, language = {{ENG}}, abstract = {{I}ntroduction: {T}he living environment affects general health and may influence cognitive aging; however, the relationships between neighborhood characteristics and dementia are still poorly understood. {M}ethods: {W}e used data from a {F}rench population-based prospective study (the {T}hree-{C}ity cohort) that included 7016 participants aged 65 years and older with a 12-year follow-up. {W}e used principal components analysis of neighborhood composition indicators to construct the {T}hree-{C}ity deprivation score. {T}o study its impact on dementia incidence, we performed survival analyses using a marginal {C}ox model to take into account intraneighborhood correlations. {A}s interaction with sex was significant, analyses were stratified by sex. {R}esults: {E}ven after controlling on individual factors, women living in deprived neighborhoods were at higher risk of dementia (hazard ratio = 1.29, 95% confidence interval 1.00-1.67) and {A}lzheimer's disease (hazard ratio = 1.42, 95% confidence interval 1.09-1.84). {N}o association was found for men. {D}iscussion: {L}iving in a deprived neighborhood is associated with higher risk of dementia in women.}, keywords = {{D}ementia ; {S}ocioeconomic status ; {L}iving environment ; {N}eighborhood ; {D}eprivation score ; {G}ender ; {FRANCE} ; {BORDEAUX} ; {DIJON} ; {MONTPELLIER}}, booktitle = {}, journal = {{A}lzheimers and {D}ementia}, volume = {14}, numero = {4}, pages = {473--482}, ISSN = {1552-5260}, year = {2018}, DOI = {10.1016/j.jalz.2017.09.015}, URL = {https://www.documentation.ird.fr/hor/fdi:010072810}, }