@article{fdi:010072791, title = {{P}revalence and associated risk factors of malaria in the first trimester of pregnancy : a preconceptional cohort study in {B}enin}, author = {{A}ccrombessi, {M}. and {F}ievet, {N}adine and {Y}ovo, {E}. and {C}ottrell, {G}illes and {A}gbota, {G}. and {M}assougbodji, {A}. and {C}ot, {M}ichel and {B}riand, {V}al{\'e}rie}, editor = {}, language = {{ENG}}, abstract = {{B}ackground. {T}here is a lack of data on the burden of malaria in the first trimester of pregnancy in {A}frica, mainly because pregnant women generally attend the maternity clinic late. {B}ed nets are rarely provided to women before the second trimester of pregnancy and intermittent preventive treatment with sulfadoxine-pyrimethamine is not recommended before the second trimester, leaving women insufficiently or not protected in early pregnancy.& para;& para;{M}ethods. {T}o assess the burden of first trimester malaria, 387 women were followed up monthly from preconception to delivery. {T}hey were screened for malaria monthly from early pregnancy until delivery. {A} logistic multilevel model was used to assess maternal factors associated with malaria during the first trimester.& para;& para;{R}esults. {T}he proportion of women with at least 1 microscopic malaria infection during the first trimester of pregnancy was 20.8%. {W}omen infected with malaria preconception were more likely to be infected during the first trimester (adjusted odds ratio: 2.68; 95% confidence interval, 1.24-5.78). {E}arly gestational age was also positively correlated with malaria infection.& para;& para;{C}onclusions. {U}sing a preconceptional study design, we showed that malaria was highly prevalent in early pregnancy. {T}his calls for the assessment of new strategies that could protect women as soon as the first trimester.}, keywords = {{M}alaria ; first trimester ; pregnancy ; cohort ; risk factors ; {B}enin ; {BENIN}}, booktitle = {}, journal = {{J}ournal of {I}nfectious {D}iseases}, volume = {217}, numero = {8}, pages = {1309--1317}, ISSN = {0022-1899}, year = {2018}, DOI = {10.1093/infdis/jiy009}, URL = {https://www.documentation.ird.fr/hor/fdi:010072791}, }