@article{fdi:010072757,
  title = {{S}ubclinical inflammation affects iron and vitamin {A} but not zinc status assessment in {S}enegalese children and {C}ambodian children and women [+ {E}rratum in {P}ublic {H}ealth {N}utrition.2018, vol. 21, no 11, p. 2160]},
  author = {{F}iorentino, {M}arion and {P}erignon, {M}. and {K}uong, {K}. and {C}hamnan, {C}. and {B}erger, {J}acques and {W}ieringa, {F}ranck},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjective: {T}o assess the impact of the acute-phase response ({APR}) during inflammation on {F}e, {Z}n and vitamin {A} biomarkers to allow accurate evaluation of micronutrient status in populations. {D}esign: {F}erritin ({FER}), soluble transferrin receptor ({T}f{R}), retinol-binding protein ({RBP}), {Z}n, alpha-acid glycoprotein and {C}-reactive protein concentrations were measured. {C}orrection factors ({CF}) for each biomarker were calculated as the ratio for groups at different stages of inflammation v. the reference group without inflammation. {S}etting/{S}ubjects: {S}enegalese (n 594) and {C}ambodian schoolchildren (n 2471); {C}ambodian women of reproductive age (n 2117). {R}esults: {T}f{R} was higher during the incubation phase ({CF}=1.17) and lower during early and late convalescence ({CF}=0.87 and 0.78). {FER} was higher during all phases ({CF}=0.83, 0.48 and 0.65, respectively). {RBP} was higher during incubation ({CF}=0.88) and lower during early convalescence ({CF}=1.21). {N}o effect of inflammation on {Z}n status was found. {C}onclusions: {I}nflammation led to overestimation of {F}e status and underestimation of vitamin {A} status. {T}he response of the biomarker for vitamin {A} status to inflammation depended on the vitamin {A} status of the populations. {S}urprisingly, the assessment of {Z}n status was hardly affected by inflammation. {D}ifferent phases of the {APR} had opposite effects on the assessment of {F}e status using {T}f{R}. {M}ore research is needed to define the correct methods to adjust for inflammation in nutritional studies.},
  keywords = {{I}nflammation ; {F}erritin ; {S}oluble transferrin receptor ; {Z}inc ; {R}etinol-binding protein ; {SENEGAL} ; {CAMBODGE}},
  booktitle = {},
  journal = {{P}ublic {H}ealth {N}utrition},
  volume = {21},
  numero = {7},
  pages = {1266--1277 [+ {E}rratum in {P}ublic {H}ealth {N}utrition.2018, vol. 21, no 11, p. 2160]},
  ISSN = {1368-9800},
  year = {2018},
  DOI = {10.1017/s1368980017003809},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072757},
}