@article{fdi:010072721,
  title = {{T}argeted application of an organophosphate-based paint applied on windows and doors against {A}nopheles coluzzii resistant to pyrethroids under real life conditions in {V}allee du {K}ou, {B}urkina {F}aso ({W}est {A}frica)},
  author = {{P}oda, {S}. {B}. and {S}oma, {D}. {D}. and {H}ien, {A}. and {N}amountougou, {M}. and {G}nankin{\'e}, {O}. and {D}iabat{\'e}, {A}. and {F}ournet, {F}lorence and {B}aldet, {T}. and {M}as-{C}oma, {S}. and {M}osqueira, {B}. and {D}abir{\'e}, {R}. {K}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {A} novel strategy applying an organophosphate-based insecticide paint on doors and windows in combination with long-lasting insecticide-treated nets ({LLIN}s) was tested for the control of pyrethroid-resistant malaria vectors in a village setting in {V}allee du {K}ou, a rice-growing area west of {B}urkina {F}aso. {M}ethods: {I}nsecticide {P}aint {I}nesfly 5{A} {IGR} ({TM}), comprised of two organophosphates and an insect growth regulator, was applied to doors and windows and tested in combination with pyrethroid-treated {LLIN}s. {T}he killing effect was monitored for 5 months by early morning collections of anophelines and other culicids. {T}he residual efficacy was evaluated monthly by {WHO} bioassays using {A}nopheles gambiae '{K}isumu' and local populations of {A}nopheles coluzzii resistant to pyrethroids. {T}he spatial mortality efficacy ({SME}) at distances of 1 m was also assessed against pyrethroid-susceptible and -resistant malaria vectors. {T}he frequency of {L}1014{F} kdr and {A}ce-1({R}) {G}119{S} mutations was, respectively, reported throughout the study. {T}he {I}nsecticide {P}aint {I}nesfly 5{A} {IGR} had been tested in past studies yielding a long-term mortality rate of 80% over 12 months against {A}n. coluzzii, the local pyrethroid-resistant malaria vector. {T}he purpose of the present study is to test if treating smaller, targeted surfaces (e.g. doors and windows) was also efficient in killing malaria vectors. {R}esults: {T}reating windows and doors alone yielded a killing efficacy of 100% for 1 month against {A}n. coluzzii resistant to pyrethroids, but efficacy reduced quickly afterwards. {L}ikewise, {WHO} cone bioassays yielded mortalities of 80-100% for 2 months but declined to 90 and 40% 2 and 3 months after treatment, respectively. {M}osquitoes exposed to insecticide paint-treated surfaces at distances of 1 m, yielded mortality rates of about 90-80% against local pyrethroids-resistant {A}n. coluzzii during the first 2 months, but decreased to 30% afterwards. {A}nopheles coluzzii was reported to be exclusively the local malaria vector and resistant to pyrethroids with high {L}1014 kdr frequency. {C}onclusion: {T}he combination of insecticide paint on doors and windows with {LLIN}s yielded high mortality rates in the short term against wild pyrethroid-resistant malaria vector populations. {A} high {SME} was observed against laboratory strains of pyrethroid-resistant malaria vectors placed for 30 min at 1 m from the treated/control walls. {T}he application of the insecticide paint on doors and windows led to high but short-lasting mortality rates. {T}he strategy may be an option in a context where low cost, rapid responses need to be implemented in areas where malaria vectors are resistant to pyrethroids.},
  keywords = {{M}osquito control ; {I}nsecticide resistance ; {O}rganophosphates ; {I}nsecticide ; paint ; {B}urkina {F}aso ; {A}frica ; {W}estern ; {BURKINA} {FASO} ; {KOU} {VALLEE}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {17},
  numero = {},
  pages = {art. 136 [9 p.]},
  ISSN = {1475-2875},
  year = {2018},
  DOI = {10.1186/s12936-018-2273-x},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072721},
}