@article{fdi:010072499,
  title = {{M}olecular characterization of complete genome of a canine distemper virus associated with fatal infection in dogs in {G}abon, {C}entral {A}frica},
  author = {{M}aganga, {G}. {D}. and {L}abouba, {I}. and {N}goubangoye, {B}. and {N}kili-{M}eyong, {A}. {A}. and {O}ndo, {D}. {O}. and {L}eroy, {E}ric and {B}erthet, {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}anine distemper ({CD}) is the most deadly disease in dogs with mortality rates reaching 50%. {T}he pathological agent, the {CD} virus ({CDV}), generally causes a severe systemic disease, although the nervous form can coexist with the acute catarrhal form in the same individual. {I}n this study, we describe an outbreak of 18 cases of {CD} that occurred in 2015 in a {G}erman {S}hepherd dog population in northwestern {G}abon. {I}n addition, we determined the sequence of the {CDV} genotype associated with this fatal distemper infection in {G}abon and compared it with other published {CDV} sequences. {T}he {CDV} was detected using {RT}-{PCR} on c{DNA} from {RNA} of harvested brains and other organs. {T}he identification was confirmed by sequencing amplicons. {M}oreover, we obtained the whole genome sequence using high-throughput sequencing. {P}hylogenetic analysis revealed that {G}abonese {CDV} strain clustered with {E}uropean strains belonging to the {E}urope genotype. {T}his study provided the first molecular detection of the {CDV} strain associated with this fatal distemper infection in {C}entral {A}frica region.},
  keywords = {{CDV} ; {H}igh-throughput sequencing ; {E}urope genotype ; {C}entral {A}frica ; {GABON}},
  booktitle = {},
  journal = {{V}irus {R}esearch},
  volume = {247},
  numero = {},
  pages = {21--25},
  ISSN = {0168-1702},
  year = {2018},
  DOI = {10.1016/j.virusres.2018.01.012},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072499},
}