@article{fdi:010072486,
  title = {{R}ethinking the extrinsic incubation period of malaria parasites},
  author = {{O}hm, {J}. {R}. and {B}aldini, {F}. and {B}arreaux, {P}. and {L}ef{\`e}vre, {T}hierry and {L}ynch, {P}. {A}. and {S}uh, {E}. and {W}hitehead, {S}. {A}. and {T}homas, {M}. {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he time it takes for malaria parasites to develop within a mosquito, and become transmissible, is known as the extrinsic incubation period, or {EIP}. {EIP} is a key parameter influencing transmission intensity as it combines with mosquito mortality rate and competence to determine the number of mosquitoes that ultimately become infectious. {I}n spite of its epidemiological significance, data on {EIP} are scant. {C}urrent approaches to estimate {EIP} are largely based on temperature-dependent models developed from data collected on parasite development within a single mosquito species in the 1930s. {T}hese models assume that the only factor affecting {EIP} is mean environmental temperature. {H}ere, we review evidence to suggest that in addition to mean temperature, {EIP} is likely influenced by genetic diversity of the vector, diversity of the parasite, and variation in a range of biotic and abiotic factors that affect mosquito condition. {W}e further demonstrate that the classic approach of measuring {EIP} as the time at which mosquitoes first become infectious likely misrepresents {EIP} for a mosquito population. {W}e argue for a better understanding of {EIP} to improve models of transmission, refine predictions of the possible impacts of climate change, and determine the potential evolutionary responses of malaria parasites to current and future mosquito control tools.},
  keywords = {{M}alaria ; {M}osquito ; {E}xtrinsic incubation period ; {EIP} ; {T}emperature},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {11},
  numero = {},
  pages = {art. 178 [9 p.]},
  ISSN = {1756-3305},
  year = {2018},
  DOI = {10.1186/s13071-018-2761-4},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072486},
}