@article{fdi:010072454,
  title = {{O}perationalization of the test and not treat strategy to accelerate the elimination of onchocerciasis and lymphatic filariasis in {C}entral {A}frica},
  author = {{K}amgno, {J}. and {N}ana-{D}jeunga, {H}. {C}. and {P}ion, {S}{\'e}bastien and {C}hesnais, {C}{\'e}dric and {K}lion, {A}. {D}. and {M}ackenzie, {C}. {D}. and {N}utman, {T}. {B}. and {B}oussinesq, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{A}fter 30 years of treatment with {M}ectizan (ivermectin), cutaneous and ocular complications of {O}nchocerca volvulus infection are now scarce in endemic communities. {I}ndeed, transmission has been interrupted and the volvulus- associated disease has disappeared in some {A}frican foci. {D}espite this success, onchocerciasis elimination in {L}oa loa co-endemic areas is still constrained by severe adverse events ({SAE}s) occurring after ivermectin treatment in some individuals harbouring very high {L}. loa microfilaremia. {O}ne approach towards the prevention of these {SAE}s is to identify individuals with high {L}. loa microfilaremia and exclude them from ivermectin treatment. {T}he development of the {L}oa{S}cope has provided the tool that underlies this test and not treat ({T}a{NT}) strategy. {T}he first successful {T}a{NT} campaign was conducted in a {L}. loa highly endemic focus in {C}ameroon in 2015 without any {SAE}s. {T}o accomplish this within a research setting, 60 people were deployed for this campaign, making this 'research' strategy not sustainable from a cost perspective. {W}e describe here a way of reducing the cost of the {T}a{NT} strategy with a smaller team (three people) selected within affected communities. {W}e also suggest the organization of a {T}a{NT} campaign in affected countries.},
  keywords = {{T}est and not treat ; {O}nchocerciasis ; {L}ymphatic filariasis ; {L}oiasis ; {C}entral {A}frica ; {CAMEROUN} ; {AFRIQUE} {CENTRALE}},
  booktitle = {},
  journal = {{I}nternational {H}ealth},
  volume = {10},
  numero = {1},
  pages = {i49--i53},
  ISSN = {1876-3413},
  year = {2018},
  DOI = {10.1093/inthealth/ihx051},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072454},
}