@article{fdi:010072403, title = {{E}mergence of {W}esselsbron virus among black rat and humans in {E}astern {S}enegal in 2013}, author = {{D}iagne, {M}. {M}. and {F}aye, {M}. and {F}aye, {O}. and {S}ow, {A}. and {B}alique, {F}. and {S}embene, {M}. and {G}ranjon, {L}aurent and {H}andschumacher, {P}ascal and {F}aye, {O}. and {D}iallo, {M}. and {S}all, {A}. {A}.}, editor = {}, language = {{ENG}}, abstract = {{W}esselsbron disease is a neglected mosquito transmitted {F}lavivirus infection that causes abortions and has teratogenic effects on sheep and cattle in {A}frica. {H}uman can also be infected. {T}he detection of human or animal cases is complicated by the non-specific symptoms close to {R}ift {V}alley {F}ever ({RVF}) in domestic livestock species or {D}engue like syndrome in humans. {T}hen, these detections are usually made during {RVF} investigations in sheep. {T}hese domestic animals should take a role in the life cycle of the virus but some evidences of {W}esselsbron virus ({WSLV}) presence in wild animals suggest that the latter may be involved in the virus maintenance in nature. {H}owever, the reservoir status of wild vertebrate in general and rodents particularly for {WSLV} is only based on an isolation from a {C}ape short-eared gerbil in southern {A}frica. {M}ost of {WSLV} isolations are from southern parts of {A}frica even if it has been found in western and central {A}frica or {M}adagascar. {I}n {S}enegal, there are serological evidences of {WSLV} circulation in human since the 1970s and some isolations, the last one of which dates back in 1992. {D}espite the detection of the virus on mosquitoes until the 2000s in different parts of the country, no new human case has been noted. {I}n this paper, we report the {WSLV} re-emergence in eastern {S}enegal in 2013 with 2 human cases and its first isolation from a black rat {R}attus rattus. {S}equencing analyses show the circulation of the same strain between these humans and the commensal rodent. {T}he putative impact on {WSLV} transmission to human populations could be more important if the reservoir status of the black rat is confirmed. {F}ocused survey in human populations, specific entomological and mammalogical investigations would permit a better understanding of the life cycle of the virus and its impact on public health.}, keywords = {{W}esselsbron virus ; {R}odents ; {B}lack rat ; {E}astern {S}enegal ; {SENEGAL}}, booktitle = {}, journal = {{O}ne {H}ealth}, volume = {3}, numero = {}, pages = {23--28}, ISSN = {2352-7714}, year = {2017}, DOI = {10.1016/j.onehlt.2017.02.001}, URL = {https://www.documentation.ird.fr/hor/fdi:010072403}, }