@article{fdi:010072070,
  title = {{S}patial and temporal dynamics of malaria in {M}adagascar},
  author = {{I}hantamalala, {F}. {A}. and {R}akotoarimanana, {F}. {M}. {J}. and {R}amiadantsoa, {T}. and {R}akotondramanga, {J}. {M}. and {P}ennober, {G}. and {R}akotomanana, {F}. and {C}auchemez, {S}. and {M}etcalf, {C}. {J}. {E}. and {H}erbreteau, {V}incent and {W}esolowski, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {M}alaria is one of the primary health concerns in {M}adagascar. {B}ased on the duration and intensity of transmission, {M}adagascar is divided into five epidemiological strata that range from low to mesoendemic transmission. {I}n this study, the spatial and temporal dynamics of malaria within each epidemiological zone were studied. {M}ethods: {T}he number of reported cases of uncomplicated malaria from 112 health districts between 2010 and 2014 were compiled and analysed. {F}irst, a {S}tandardized {I}ncidence {R}atio was calculated to detect districts with anomalous incidence compared to the stratum-level incidence. {B}uilding on this, spatial and temporal malaria clusters were identified throughout the country and their variability across zones and over time was analysed. {R}esults: {T}he incidence of malaria increased from 2010 to 2014 within each stratum. {A} basic analysis showed that districts with more than 50 cases per 1000 inhabitants are mainly located in two strata: {E}ast and {W}est. {L}ower incidence values were found in the {H}ighlands and {F}ringe zones. {T}he standardization method revealed that the number of districts with a higher than expected numbers of cases increased through time and expanded into the {H}ighlands and {F}ringe zones. {T}he cluster analysis showed that for the endemic coastal region, clusters of districts migrated southward and the incidence of malaria was the highest between {J}anuary and {J}uly with some variation within strata. {C}onclusion: {T}his study identified critical districts with low incidence that shifted to high incidence and district that were consistent clusters across each year. {T}he current study provided a detailed description of changes in malaria epidemiology and can aid the national malaria programme to reduce and prevent the expansion of the disease by targeting the appropriate areas.},
  keywords = {{M}alaria ; {M}adagascar ; {S}trata ; {S}tandardized {I}ncidence {R}atio ; {S}a{TS}can ; {MADAGASCAR}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {17},
  numero = {},
  pages = {art. 58 [13 p.]},
  ISSN = {1475-2875},
  year = {2018},
  DOI = {10.1186/s12936-018-2206-8},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072070},
}