@article{fdi:010071955,
  title = {{P}lasmodium falciparum infection early in pregnancy has profound consequences for fetal growth},
  author = {{S}chmiegelow, {C}. and {M}atondo, {S}. and {M}inja, {D}. {T}. {R}. and {R}esende, {M}. and {P}ehrson, {C}. and {N}ielsen, {B}. {B}. and {O}lomi, {R}. and {N}ielsen, {M}. {A}. and {D}eloron, {P}hilippe and {S}alanti, {A}. and {L}usingu, {J}. and {T}heander, {T}. {G}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}alaria during pregnancy constitutes a large health problem in areas of endemicity. {T}he {W}orld {H}ealth {O}rganization recommends that interventions are initiated at the first antenatal visit, and these improve pregnancy outcomes. {T}his study evaluated fetal growth by ultrasonography and birth outcomes in women who were infected prior to the first antenatal visit (gestational age, < 120 days) and not later in pregnancy. {C}ompared with uninfected controls, women with early {P}lasmodium falciparum exposure had retarded intrauterine growth between gestational ages of 212 and 253 days (difference between means, 107 g [95% confidence interval {{CI}}, 26-188]; {P} = .0099) and a shorter pregnancy duration (difference between means, 6.6 days [95% {CI}, 1.0-112.5]; {P} = .0087). {T}he birth weight (difference between means, 221 g [95% {CI}, 6-436]; {P} = .044) and the placental weight (difference between means, 84 g [95% {CI}, 18-150]; {P} = .013) at term were also reduced. {T}he study suggests that early exposure to {P}. falciparum, which is not targeted for prevention by current control strategies, has a profound impact on fetal growth, pregnancy duration, and placental weight at term.},
  keywords = {{M}alaria ; {P}lasmodium falciparum ; pregnancy ; fetal growth ; birth weight ; placenta},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {216},
  numero = {12},
  pages = {1601--1610},
  ISSN = {0022-1899},
  year = {2017},
  DOI = {10.1093/infdis/jix530},
  URL = {https://www.documentation.ird.fr/hor/fdi:010071955},
}