@article{fdi:010071442,
  title = {{I}nsights into reductive dechlorination of triclocarban in river sediments : field measurements and in vitro mechanism investigations},
  author = {{S}ouchier, {M}. and {C}asellas, {C}. and {I}ngrand, {V}. and {C}hiron, {S}erge},
  editor = {},
  language = {{ENG}},
  abstract = {{T}riclocarban ({TCC}) reductive dechlorination was investigated using a combination of field and laboratory experiments. {F}ield monitoring revealed that {TCC} reductive dechlorination in river sediments leads to formation of two isomers of its lesser chlorinated congener namely 3,4'-dichlorocarbanilide and 4,4'-dichlorocarbanilide. {M}onochlorocarbanilide was not detected in sediments supporting that transformation of dichlorocarbanilide into monochlorocarbanilide is the rate limiting step of {TCC} dechlorination. {I}n vitro experiments were conducted to study {TCC} potential reductive dechlorination mechanisms. {T}hese experiments demonstrated that 4,4'-dichlorocarbanilide was specifically formed upon a nucleophilic addition reaction under anaerobic conditions. {T}he 3,4'-diclorocarbanilide was formed upon a two steps radical mechanism under aerobic conditions which includes {TCC} activation by one electron oxidation followed by a nucleophilic substitution reaction with glutathione. {I}n vitro results suggested that strict anaerobic conditions might not be required for {TCC} reductive dechlorination in the environment. {M}oreover, in vitro reactions were performed using biomimetic or enzymatic systems supposing that {TCC} dechlorination might occur through microbial action in situ. {M}easured dichlorocarbanilide isomers/triclocarban ratios were used to evaluate the relative significance of both dechlorination pathways and the pathway leading to 3,4'-dichlorocarbanilide was found significant in all investigated river sediment samples.},
  keywords = {{T}riclocarban ; {S}ediment ; {R}eductive dechlorination ; {N}ucleophilic substitution ; {N}ucleophilic addition},
  booktitle = {},
  journal = {{C}hemosphere},
  volume = {144},
  numero = {},
  pages = {425--432},
  ISSN = {0045-6535},
  year = {2016},
  DOI = {10.1016/j.chemosphere.2015.08.083},
  URL = {https://www.documentation.ird.fr/hor/fdi:010071442},
}