Publications des scientifiques de l'IRD

Boushab B. M., Fall F. Z. M., Vadel Tkocm, Melainine Mloc, Maazouz M. V., Savadogo M., Basco Leonardo. (2017). Mucocutaneous manifestations in human immunodeficiency virus (HIV)-infected patients in Nouakchott, Mauritania. International Journal of Dermatology, 56 (12), p. 1421-1424. ISSN 0011-9059.

Titre du document
Mucocutaneous manifestations in human immunodeficiency virus (HIV)-infected patients in Nouakchott, Mauritania
Année de publication
2017
Type de document
Article référencé dans le Web of Science WOS:000415003200015
Auteurs
Boushab B. M., Fall F. Z. M., Vadel Tkocm, Melainine Mloc, Maazouz M. V., Savadogo M., Basco Leonardo
Source
International Journal of Dermatology, 2017, 56 (12), p. 1421-1424 ISSN 0011-9059
BackgroundMucocutaneous manifestations are one of the first clinical signs in patients infected with human immunodeficiency virus (HIV). To the best of our knowledge, there has been no previous study describing dermatologic manifestations in Mauritanians infected with HIV. The aim of the present study was to determine the profiles of mucocutaneous manifestations in relation to CD4 T cell count in HIV-positive Mauritanian patients. MethodsA total of 86 adult patients aged > 18 years old attending the Ambulatory Treatment Center of the National Hospital of Nouakchott, Mauritania, with newly diagnosed HIV and who were not under antiretroviral treatment were included in the study in 2015. Dermatologic manifestations were documented before initiating antiretroviral treatment. ResultsMost of the included patients were in clinical stage 3 of the World Health Organization classification at initial diagnosis, with the mean CD4 T cell count ( SD) of 514 +/- 319 cells/mm(3) (range, 2-1328 cells/mm(3)), and 19 of 86 (22.1%) patients had CD4 T cell counts below 200 cells/mm(3). More than half (64%) of newly diagnosed HIV-infected patients had dermatoses, including the following: pruritic papular eruption (44.2%), seborrheic dermatitis (4.7%), Kaposi's sarcoma (3.5%), extensive xerosis cutis (2.3%), drug-induced skin reactions (1.2%), and various infectious dermatoses (dermatophyte infections [16.3%], oral candidiasis [11.6%], herpes zoster [8.1%], and scabies [2.3%]). A low CD4 T cell count (< 200 cells/mm(3)) was significantly correlated (P < 0.05) with the presence of following dermatoses: dermatophytosis, oral candidiasis, Kaposi's sarcoma, seborrheic dermatitis, and extensive xerosis cutis. ConclusionMucocutaneous lesions occur throughout the course of HIV infection, and dermatologic findings in Mauritanian HIV-positive patients are similar to those of patients in other countries. Early detection of skin disorders in some patients may help establish the diagnosis of HIV and management of HIV-associated diseases, limiting the cost of care in low-resource countries.
Plan de classement
Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
MAURITANIE ; NOUAKCHOTT
Localisation
Fonds IRD [F B010071359]
Identifiant IRD
fdi:010071359
Contact