@article{fdi:010071350, title = {{G}alba truncatula and {F}asciola hepatica : genetic costructures and interactions with intermediate host dispersal}, author = {{C}orrea, {A}. {C}. and {D}e {M}eeûs, {T}hierry and {D}reyfuss, {G}. and {R}ondelaud, {D}. and {H}urtrez-{B}ousses, {S}.}, editor = {}, language = {{ENG}}, abstract = {{A}ntagonistic interactions between hosts and parasites are key structuring forces in natural populations. {D}emographic factors like extinction, migration and the effective population size shape host-parasite metapopulational dynamics. {T}herefore, to understand the evolution of host-parasite systems it is necessary to study the distribution of the genetic variation of both entities simultaneously. {I}n this paper, we investigate the population genetics co-structure of parasites and hosts within a metapopulation of the liver fluke, {F}asciola hepatica, and two of its intermediate hosts, the main intermediate host in {E}urope, {G}alba truncatula, and a new intermediate host, {O}mphiscola glabra, in {C}entral {F}rance. {O}ur results reveal an absence of specificity of flukes as regard to the two alternative hosts though {O}. glabra shows higher prevalence of {F}. hepatica. {H}ost and parasites displayed contrasting population genetics structure with very small, highly inbred (selfing) and strongly isolated {G}. truncatula populations and much bigger, panmictic and more dispersive {F}. hepatica. {T}his could indicate a local adaptation of the parasite and a local maladaptation of the host. {W}e also unveil a parasite-mediated biased population genetics structure suggesting that infected {G}. truncatula disperse more; have higher dispersal survival than uninfected snails or, more likely, that immigrant snails are infected more often than local snails (local parasites are less adapted to local hosts). {F}inally, an absence, or at least an ambiguous signature of isolation by distance was observed in both host and parasite population. {A} very weak migration rate for {G}. truncatula provides a reasonable explanation for this ambiguous result. {A}lternatively, smaller sample sizes combined with modest migration rates might explain the difficulties to unveil the signal in {F}. hepatica.}, keywords = {{F}asciola hepatica ; {G}alba truncatula ; {O}mphiscola glabra ; {G}enetic variability ; {S}elfing ; {L}ocal adaptation ; {FRANCE}}, booktitle = {}, journal = {{I}nfection {G}enetics and {E}volution}, volume = {55}, numero = {}, pages = {186--194}, ISSN = {1567-1348}, year = {2017}, DOI = {10.1016/j.meegid.2017.09.012}, URL = {https://www.documentation.ird.fr/hor/fdi:010071350}, }