@article{fdi:010071272, title = {{C}rossover trial to test the acceptability of a locally produced lipid-based nutrient supplement ({LNS}) for children under 2 years in {C}ambodia : a study protocol}, author = {{B}org, {B}. and {M}ihrshahi, {S}. and {G}riffin, {M}. and {C}hamnan, {C}. and {L}aillou, {A}. and {W}ieringa, {F}ranck}, editor = {}, language = {{ENG}}, abstract = {{I}ntroduction {T}he acceptability and efficacy of existing ready-to-use supplementary and therapeutic foods has been low in {C}ambodia, thus limiting success in preventing and treating malnutrition among {C}ambodian children. {I}n that context, {UNICEF} and {IRD} have developed a locally produced, multiple micronutrient fortified lipid-based nutrient supplement. {T}his food is innovative, in that it uses fish instead of milk as the animal source food. {V}ery few supplementary foods have non-milk animal source foods, and in addition they have not been widely tested. {T}his trial will assess the novel food's acceptability to children and caregivers. {M}ethods and analysis {T}his is a cluster-randomised, incomplete block, 4x4 crossover design with no blinding. {I}t will take place in four sites in a community setting in periurban {P}hnom {P}enh. {H}ealthy children aged 9-23 months (n=100) will eat each of four foods for 3 days at a time. {T}he amount they consume will be measured, and at the end of each 3-day set, caregivers will assess how well their child liked the food. {A}fter 12 days, caregivers themselves will do a sensory test of the 4 foods and will rank them in terms of preference. {E}thics and dissemination {E}thical clearance was received from the {U}niversity of {Q}ueensland {M}edical {R}esearch {E}thics {C}ommittee (2014001070) and from {C}ambodia's {N}ational {E}thics {C}ommittee for {H}ealth {R}esearch (03/8 {NECHR}). {R}egistration {C}linical{T}rials.gov, identifier: {LNS}-{CAMB}-{INFANTS}; {NCT}02257437. {P}re-results.}, keywords = {{CAMBODGE}}, booktitle = {}, journal = {{BMJ} {O}pen}, volume = {7}, numero = {9}, pages = {e015958 [6 p.]}, ISSN = {2044-6055}, year = {2017}, DOI = {10.1136/bmjopen-2017-015958}, URL = {https://www.documentation.ird.fr/hor/fdi:010071272}, }