Publications des scientifiques de l'IRD

Dickson L. B., Jiolle D., Minard G., Moltini-Conclois I., Volant S., Ghozlane A., Bouchier C., Ayala Diego, Paupy Christophe, Moro C. V., Lambrechts L. (2017). Carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector. Science Advances, 3 (8), p. e1700585 [14 p.]. ISSN 2375-2548.

Titre du document
Carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector
Année de publication
2017
Type de document
Article référencé dans le Web of Science WOS:000411589900047
Auteurs
Dickson L. B., Jiolle D., Minard G., Moltini-Conclois I., Volant S., Ghozlane A., Bouchier C., Ayala Diego, Paupy Christophe, Moro C. V., Lambrechts L.
Source
Science Advances, 2017, 3 (8), p. e1700585 [14 p.] ISSN 2375-2548
Conditions experienced during larval development of holometabolous insects can affect adult traits, but whether differences in the bacterial communities of larval development sites contribute to variation in the ability of insect vectors to transmit human pathogens is unknown. We addressed this question in the mosquito Aedes aegypti, a major arbovirus vector breeding in both sylvatic and domestic habitats in Sub-Saharan Africa. Targeted metagenomics revealed differing bacterial communities in the water of natural breeding sites in Gabon. Experimental exposure to different native bacterial isolates during larval development resulted in significant differences in pupation rate and adult body size but not life span. Larval exposure to an Enterobacteriaceae isolate resulted in decreased antibacterial activity in adult hemolymph and reduced dengue virus dissemination titer. Together, these data provide the proof of concept that larval exposure to different bacteria can drive variation in adult traits underlying vectorial capacity. Our study establishes a functional link between larval ecology, environmental microbes, and adult phenotypic variation in a holo-metabolous insect vector.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
GABON ; AFRIQUE SUBSAHARIENNE
Localisation
Fonds IRD [F B010071227]
Identifiant IRD
fdi:010071227
Contact