@article{fdi:010071005,
  title = {{T}he unexpected role of bioaerosols in the {O}xidative {P}otential of {PM}},
  author = {{S}amake, {A}. and {U}zu, {G}a{\¨e}lle and {M}artins, {J}. {M}. {F}. and {C}alas, {A}. and {V}ince, {E}. and {P}arat, {S}. and {J}affrezo, {J}. {L}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ioaerosols represent up to 15-25% of {PM} by mass, but there is currently no assessment of their impact on {O}xidative {P}otential ({OP}), or capacity of particulate matter ({PM}) to produce damaging oxidative reactions in the human lungs. {H}ere, the {OP} of selected bioaerosols (bacteria cells vs fungal spores) was assessed through the cell-free {DTT} assay. {R}esults show that bioaerosols induce {R}eactive {O}xygen {S}pecies ({ROS}) production, varying along the microorganism type, species, and concentration. {F}ungal spores show up to 10 times more {ROS} generation than bacterial cells. {A}t the highest concentrations, fungal spores present as much oxidative reactivity as the most redox-active airborne chemicals ({C}opper, {N}aphtoquinone). {M}oreover, bioaerosols substantially influence {OP} of ambient {PM} and that of its chemical constituents: in presence of {A}. fumigatus spores, the {OP} of {C}u/{NQ} is increased by a factor of 2 to 5, whereas, 10(4) and 10(5) {S}. epidermidis bacterial cells. m{L}(-1) halves the {OP} of {C}u/{NQ}. {F}inally, viable and gamma-rays-killed model bioaerosols present similar oxidative reactivity, suggesting a metabolism-independent cellular mechanism. {T}hese results reveal the importance of bioaerosols for {PM} reactivity. {PM} toxicity can be modified due to bioaerosols contribution or by their ability to modulate the {OP} of toxic chemicals present in {PM}.},
  keywords = {},
  booktitle = {},
  journal = {{S}cientific {R}eports - {N}ature},
  volume = {7},
  numero = {},
  pages = {art. 10978 [10 p.]},
  ISSN = {2045-2322},
  year = {2017},
  DOI = {10.1038/s41598-017-11178-0},
  URL = {https://www.documentation.ird.fr/hor/fdi:010071005},
}