@article{fdi:010070960,
  title = {{T}he implementation of long-lasting insecticidal bed nets has differential effects on the genetic structure of the {A}frican malaria vectors in the {A}nopheles gambiae complex in {D}ielmo, {S}enegal},
  author = {{S}ougoufara, {S}. and {S}okhna, {C}heikh and {D}iagne, {N}. and {D}oucour{\'e}, {S}. and {S}emb{\`e}ne, {P}. {M}. and {H}arry, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {M}osquitoes belonging to the {A}nopheles gambiae complex are the main vectors of malaria in sub-{S}aharan {A}frica. {A}mong these, {A}n. gambiae, {A}nopheles coluzzii and {A}nopheles arabiensis are the most efficient vectors and are largely distributed in sympatric locations. {H}owever, these species present ecological and behavioural differences that impact their vectorial capacity and complicate vector-control efforts, mainly based on long-lasting insecticidal bed nets ({LLIN}s) and indoor residual spraying ({IRS}). {I}n this study, the genetic structure of these three species in a {S}enegalese village ({D}ielmo) was investigated using microsatellite data in samples collected in 2006 before implementation of {LLIN}s, in 2008, when they were introduced, and in 2010, 2 years after the use of {LLIN}s. {R}esults: {I}n this study 611 individuals were included, namely 136 {A}n. coluzzii, 101 {A}n. gambiae, 6 {A}n. coluzzii/{A}n. gambiae hybrids and 368 {A}n. arabiensis. {A}ccording to the species, the effect of the implementation of {LLIN}s in {D}ielmo is differentiated. {P}opulations of the sister species {A}n. coluzzii and {A}n. gambiae regularly experienced bottleneck events, but without significant inbreeding. {T}he {F}st values suggested in 2006 a breakdown of assortative mating resulting in hybrids, but the introduction of {LLIN}s was followed by a decrease in the number of hybrids. {T}his suggests a decrease in mating success of hybrids, ecological maladaptation, or a lesser probability of mating between species due to a decrease in {A}n. coluzzii population size. {B}y contrast, the introduction of {LLIN}s has favoured the sibling species {A}n. arabiensis. {I}n this study, some spatial and temporal structuration between {A}n. arabiensis populations were detected, especially in 2008, and the higher genetic diversity observed could result from a diversifying selection. {C}onclusions: {T}his work demonstrates the complexity of the malaria context and shows the need to study the genetic structure of {A}nopheles populations to evaluate the effectiveness of vector-control tools and successful management of malaria vector control.},
  keywords = {{M}alaria ; {A}n. gambiae ; {A}n. coluzzii and {A}n. arabiensis ; {LLIN}s ; {G}enetic structure ; {S}enegal ; {SENEGAL} ; {DIELMO}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {16},
  numero = {},
  pages = {art. 337 [13 p.]},
  ISSN = {1475-2875},
  year = {2017},
  DOI = {10.1186/s12936-017-1992-8},
  URL = {https://www.documentation.ird.fr/hor/fdi:010070960},
}