@article{fdi:010070948, title = {{N}o evidence for manipulation of {A}nopheles gambiae, {A}n. coluzzii and {A}n. arabiensis host preference by {P}lasmodium falciparum}, author = {{N}guyen, {P}. {L}. and {V}antaux, {A}. and {H}ien, {D}. {F}. {S}. and {D}abire, {K}. {R}. and {Y}ameogo, {B}. {K}. and {G}ouagna, {L}ouis-{C}l{\'e}ment and {F}ontenille, {D}idier and {R}enaud, {F}. and {S}imard, {F}r{\'e}d{\'e}ric and {C}ostantini, {C}arlo and {T}homas, {F}. and {C}ohuet, {A}nna and {L}ef{\`e}vre, {T}hierry}, editor = {}, language = {{ENG}}, abstract = {{W}hether malaria parasites can manipulate mosquito host choice in ways that enhance parasite transmission toward suitable hosts and/or reduce mosquito attraction to unsuitable hosts (i.e. specific manipulation) is unknown. {T}o address this question, we experimentally infected three species of mosquito vectors with wild isolates of the human malaria parasite {P}lasmodium falciparum, and examined the effects of immature and mature infections on mosquito behavioural responses to combinations of calf odour, human odour and outdoor air using a dual-port olfactometer. {R}egardless of parasite developmental stage and mosquito species, {P}. falciparum infection did not alter mosquito activation rate or their choice for human odours. {T}he overall expression pattern of host choice of all three mosquito species was consistent with a high degree of anthropophily, with infected and uninfected individuals showing higher attraction toward human odour over calf odour, human odour over outdoor air, and outdoor air over calf odour. {O}ur results suggest that, in this system, the parasite may not be able to manipulate the early long-range behavioural steps involved in the mosquito host-feeding process. {F}uture studies are required to test whether malaria parasites can modify their mosquito host choice at a shorter range to enhance transmission.}, keywords = {{BURKINA} {FASO}}, booktitle = {}, journal = {{S}cientific {R}eports - {N}ature}, volume = {7}, numero = {}, pages = {art. 9415 [11 p.]}, ISSN = {2045-2322}, year = {2017}, DOI = {10.1038/s41598-017-09821-x}, URL = {https://www.documentation.ird.fr/hor/fdi:010070948}, }