@article{fdi:010070395,
  title = {{C}haracteristics of the musculoskeletal symptoms observed among survivors of {E}bola virus disease in the {P}ostebogui cohort in {G}uinea},
  author = {{P}ers, {Y}.{M}. and {S}aliou {S}ow, {M}. and {T}averne, {B}ernard and {M}arch, {L}aura and {I}zard, {S}uzanne and {E}tard, {J}ean-{F}ran{\c{c}}ois and {B}arry, {M}. and {T}our{\'e}, {A}. and {D}elaporte, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjective.: {P}revious studies show that arthralgia is the most common symptom experienced by {E}bola virus disease ({EVD}) survivors. {N}evertheless, specific analyses of rheumatological sequelea are still lacking. {M}ethods.: {T}he {P}ostebogui study is a prospective, multicentre cohort aiming to evaluate the long-term outcomes of {EVD} survivors infected during the 2014-15 outbreak in {G}uinea. {O}f the 216 participants enrolled in the study in {O}ctober 2015, 44 patients with arthralgia/myalgia underwent a physical examination by a rheumatologist (the {E}borheum cohort). {D}ata were collected using a standardized questionnaire. {R}esults.: {I}n the {E}borheum cohort, 61% of patients were female, the median age was 31.1 years, and the median time from {E}bola {T}reatment {C}entre discharge was 8.8 months. {P}ain manifestation started after {E}bola infection in all but one patient. {P}atients had mainly both mechanical and inflammatory pain (45%) and low back pain (77%). {A}ll patients reported pain in at least one peripheral joint. {P}ain in large joints was more frequently reported than in small joints (73 vs 41%). {O}ligo- and polyarticular presentations were similar, with symmetrical pain distribution. {F}urthermore, 36 patients had at least one painful 18-tender point count, most of whom reported extensive pain (n = 19) and symmetrical distribution (91%). {D}iagnoses were mainly non-specific musculoskeletal disorders (59%) and mechanical back pain (52%). {N}o polyarthritis was observed. {W}e found a higher percentage of depressed patients compared with the remaining {P}ostebogui group (42 vs 11%; {P} < 0.001). {C}onclusion.: {R}esults from the study come from the first complete rheumatological examination of a cohort of {EVD} survivors, nearly 9 months after {E}bola {T}reatment {C}entre discharge. {I}mportantly, we found that patients with arthralgia/myalgia included in the {E}borheum cohort were more likely to experience depression than survivors not reporting these symptoms, highlighting the impact of pain symptoms among survivors.},
  keywords = {{GUINEE}},
  booktitle = {},
  journal = {{R}heumatology},
  volume = {56},
  numero = {12},
  pages = {2068--2072},
  ISSN = {1462-0324},
  year = {2017},
  DOI = {10.1093/rheumatology/kex074},
  URL = {https://www.documentation.ird.fr/hor/fdi:010070395},
}