@article{fdi:010070387,
  title = {{C}ontribution of next-generation sequencing to aquatic and fish virology},
  author = {{N}kili-{M}eyong, {A}. {A}. and {B}igarr{\'e}, {L}. and {L}abouba, {I}. and {V}allaeys, {T}. and {A}varre, {J}ean-{C}hristophe and {B}erthet, {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he recent technological advances in nucleic acid sequencing, called next-generation sequencing ({NGS}), have revolutionized the field of genomics and have also influenced viral research. {A}quatic viruses, and especially those infecting fish, have also greatly benefited from {NGS} technologies, which provide a huge amount of molecular information at a low cost in a relatively short period of time. {H}ere, we review the use of the current high-throughput sequencing platforms with a special focus on the associated challenges (regarding sample preparation and bioinformatics) in their applications to the field of aquatic virology, especially for: (i) discovering novel viruses that may be associated with fish mortalities, (ii) elucidating the mechanisms of pathogenesis, and finally (iii) studying the molecular epidemiology of these pathogens.},
  keywords = {{V}iruses ; {F}ish ; {D}iagnostics {N}ext-generation sequencing ; {A}quatic virology},
  booktitle = {},
  journal = {{I}ntervirology},
  volume = {59},
  numero = {5-6},
  pages = {285--300},
  ISSN = {0300-5526},
  year = {2016},
  DOI = {10.1159/000477808},
  URL = {https://www.documentation.ird.fr/hor/fdi:010070387},
}