@article{fdi:010070310,
  title = {{C}onstructing linkage maps in the genomics era with {M}ap{D}isto 2.0},
  author = {{H}effelfinger, {C}. and {F}ragoso, {C}. {A}. and {L}orieux, {M}athias},
  editor = {},
  language = {{ENG}},
  abstract = {{M}otivation: {G}enotyping by sequencing ({GBS}) generates datasets that are challenging to handle by current genetic mapping software with graphical interface. {G}eneticists need new user-friendly computer programs that can analyze {GBS} data on desktop computers. {T}his requires improvements in computation efficiency, both in terms of speed and use of random-access memory ({RAM}). {R}esults: {M}ap{D}isto v. 2.0 is a user-friendly computer program for construction of genetic linkage maps. {I}t includes several new major features: (i) handling of very large genotyping datasets like the ones generated by {GBS}; (ii) direct importation and conversion of {V}ariant {C}all {F}ormat ({VCF}) files; (iii) detection of linkage, i.e. construction of linkage groups in case of segregation distortion; (iv) data imputation on {VCF} files using a new approach, called {LB}-{I}mpute. {F}eatures i to iv operate through inclusion of new {J}ava modules that are used transparently by {M}ap{D}isto; (v) {QTL} detection via a new {R}./qtl graphical interface.},
  keywords = {},
  booktitle = {},
  journal = {{B}ioinformatics},
  volume = {33},
  numero = {14},
  pages = {2224--2225},
  ISSN = {1367-4803},
  year = {2017},
  DOI = {10.1093/bioinformatics/btx177},
  URL = {https://www.documentation.ird.fr/hor/fdi:010070310},
}