@article{fdi:010070252, title = {{D}eforestation-driven food-web collapse linked to emerging tropical infectious disease, {M}ycobacterium ulcerans}, author = {{M}orris, {A}. {L}. and {G}u{\'e}gan, {J}ean-{F}ran{\c{c}}ois and {A}ndreou, {D}. and {M}arsollier, {L}. and {C}arolan, {K}. and {L}e {C}roller, {M}. and {S}anhueza, {D}. and {G}ozlan, {R}odolphe}, editor = {}, language = {{ENG}}, abstract = {{G}eneralist microorganisms are the agents of many emerging infectious diseases ({EID}s), but their natural life cycles are difficult to predict due to the multiplicity of potential hosts and environmental reservoirs. {A}mong 250 known human {EID}s, many have been traced to tropical rain forests and specifically freshwater aquatic systems, which act as an interface between microbe-rich sediments or substrates and terrestrial habitats. {A}long with the rapid urbanization of developing countries, population encroachment, deforestation, and land-use modifications are expected to increase the risk of {EID} outbreaks. {W}e show that the freshwater food-web collapse driven by land-use change has a nonlinear effect on the abundance of preferential hosts of a generalist bacterial pathogen, {M}ycobacterium ulcerans. {T}his leads to an increase of the pathogen within systems at certain levels of environmental disturbance. {T}he complex link between aquatic, terrestrial, and {EID} processes highlights the potential importance of species community composition and structure and species life history traits in disease risk estimation and mapping. {M}echanisms such as the one shown here are also central in predicting how human-induced environmental change, for example, deforestation and changes in land use, may drive emergence.}, keywords = {{GUYANE} {FRANCAISE}}, booktitle = {}, journal = {{S}cience {A}dvances}, volume = {2}, numero = {12}, pages = {e1600387 [7 p.]}, ISSN = {2375-2548}, year = {2016}, DOI = {10.1126/sciadv.1600387}, URL = {https://www.documentation.ird.fr/hor/fdi:010070252}, }