@article{fdi:010070210,
  title = {{E}volutionary forces affecting synonymous variations in plant genomes},
  author = {{C}lement, {Y}. and {S}arah, {G}. and {H}oltz, {Y}. and {H}oma, {F}. and {P}ointet, {S}. and {C}ontreras, {S}. and {N}abholz, {B}. and {S}abot, {F}ran{\c{c}}ois and {S}aune, {L}. and {A}rdisson, {M}. and {B}acilieri, {R}. and {B}esnard, {G}. and {B}erger, {A}. and {C}ardi, {C}. and {D}e {B}ellis, {F}. and {F}ouet, {O}. and {J}ourda, {C}. and {K}hadari, {B}. and {L}anaud, {C}. and {L}eroy, {T}. and {P}ot, {D}. and {S}auvage, {C}. and {S}carcelli, {N}ora and {T}regear, {J}ames and {V}igouroux, {Y}ves and {Y}ahiaoui, {N}. and {R}uiz, {M}. and {S}antoni, {S}. and {L}abouisse, {J}. {P}. and {P}ham, {J}ean-{L}ouis and {D}avid, {J}. and {G}lemin, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ase composition is highly variable among and within plant genomes, especially at third codon positions, ranging from {GC}-poor and homogeneous species to {GC}-rich and highly heterogeneous ones (particularly {M}onocots). {C}onsequently, synonymous codon usage is biased in most species, even when base composition is relatively homogeneous. {T}he causes of these variations are still under debate, with three main forces being possibly involved: mutational bias, selection and {GC}-biased gene conversion (g{BGC}). {S}o far, both selection and g{BGC} have been detected in some species but how their relative strength varies among and within species remains unclear. {P}opulation genetics approaches allow to jointly estimating the intensity of selection, g{BGC} and mutational bias. {W}e extended a recently developed method and applied it to a large population genomic dataset based on transcriptome sequencing of 11 angiosperm species spread across the phylogeny. {W}e found that at synonymous positions, base composition is far from mutation-drift equilibrium in most genomes and that g{BGC} is a widespread and stronger process than selection. g{BGC} could strongly contribute to base composition variation among plant species, implying that it should be taken into account in plant genome analyses, especially for {GC}-rich ones.},
  keywords = {},
  booktitle = {},
  journal = {{P}los {G}enetics},
  volume = {13},
  numero = {5},
  pages = {e1006799 [28 ]},
  ISSN = {1553-7404},
  year = {2017},
  DOI = {10.1371/journal.pgen.1006799},
  URL = {https://www.documentation.ird.fr/hor/fdi:010070210},
}