@article{fdi:010070080, title = {{I}nsight into the global evolution of {R}odentia associated {M}orbilli-related paramyxoviruses}, author = {{G}hawar, {W}. and {P}ascalis, {H}. and {B}ettaieb, {J}. and {M}elade, {J}. and {G}harbi, {A}. and {S}noussi, {M}. {A}. and {L}aouini, {D}. and {G}oodman, {S}. {M}. and {B}en {S}alah, {A}. and {D}ellagi, {K}oussay}, editor = {}, language = {{ENG}}, abstract = {{O}ne portion of the family {P}aramyxoviridae is a group of {U}nclassified {M}orbilli-{R}elated {V}iruses ({UMRV}) recently recognized in wild small mammals. {A}t a global level, the evolutionary history of these viruses is not properly understood and the relationships between {UMRV} and their hosts still remain largely unstudied. {T}he present study revealed, for the first time, that {R}odentia associated {UMRV} emerged from a common ancestor in southern {A}frica more than 4000 years ago. {S}equenced {UMRV} originating from different regions in the world, clustered into four well-supported viral lineages, which suggest that strain diversification occurred during host dispersal and associated exchanges, with purifying selection pressure as the principal evolutionary force. {I}n addition, multi-introductions on different continents and islands of {R}odentia associated {UMRV} and spillover between rodent species, most probably {R}attus rattus, were detected and indicate that these animals are implicated in the vectoring and in the worldwide emergence of this virus group. {T}he natural history and the evolution dynamics of these zoonotic viruses, originating from and hosted by wild animals, are most likely shaped by commensalism related to human activities.}, keywords = {{TUNISIE} ; {ZAMBIE} ; {AFRIQUE} {DU} {SUD} ; {TRINITE} {ET} {TOBAGO} ; {CHINE} ; {AUSTRALIE} ; {ALLEMAGNE} ; {MADAGASCAR} ; {REUNION} ; {SEYCHELLES}}, booktitle = {}, journal = {{S}cientific {R}eports - {N}ature}, volume = {7}, numero = {}, pages = {art. 1974 [12 p.]}, ISSN = {2045-2322}, year = {2017}, DOI = {10.1038/s41598-017-02206-0}, URL = {https://www.documentation.ird.fr/hor/fdi:010070080}, }