%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Scotto, C. I. %A Burger, P. %A el Khil, M. K. %A Ginouves, M. %A Prevot, G. %A Blanchet, D. %A Delprete, Piero %A Fernandez, X. %T Chemical composition and antifungal activity of the essential oil of Varronia schomburgkii (DC.) Borhidi (Cordiaceae) from plants cultivated in French Guiana %D 2017 %L fdi:010070044 %G ENG %J Journal of Essential Oil Research %@ 1041-2905 %K Varronia schomburgkii ; French Guiana ; chemical composition ; antifungal ; activities ; Candida spp ; anti-leishmanial potency %K GUYANE FRANCAISE %M ISI:000400988100003 %N 4 %P 304-312 %R 10.1080/10412905.2017.1278729 %U https://www.documentation.ird.fr/hor/fdi:010070044 %> https://www.documentation.ird.fr/intranet/publi/2017/06/010070044.pdf %V 29 %W Horizon (IRD) %X This study reports for the first time the chemical composition of the essential oil of Varronia schomburgkii (DC.) Borhidi cultivated in French Guiana. This essential oil was examined by a combination of GC/FID and GC-MS techniques and was further tested for antifungal activity against several Candida strains, as well as for anti-leishmanial activity against the reference strain Leishmania guyanensis. A total of 45 components accounting for 93.61% of the total GC/FID chromatogram were identified. The essential oil is dominated by sesquiterpenes and oxygenated sesquiterpenes among which beta-caryophyllene (46.99 +/- 0.32%) is the major one. No anti-leishmania activity could be assessed, while a strong antimicrobial activity of this essential oil was evidenced in vitro against a Candida albicans strain by the definition of a MIC value of 250 mu g/mL.V. schomburgkii essential oil might hence be considered in the future for the development of natural antifungal agents. %$ 076