@article{fdi:010069524,
  title = {{R}eproduction in {L}eishmania : a focus on genetic exchange},
  author = {{R}ougeron, {V}irginie and {D}e {M}eeûs, {T}hierry and {B}anuls, {A}nne-{L}aure},
  editor = {},
  language = {{ENG}},
  abstract = {{O}ne key process of the life cycle of pathogens is their mode of reproduction. {I}ndeed, this fundamental biological process conditions the multiplication and the transmission of genes and thus the propagation of diseases in the environment. {R}eproductive strategies of protozoan parasites have been a subject of debate for many years, principally due to the difficulty in making direct observations of sexual reproduction (i.e. genetic recombination). {T}raditionally, these parasites were considered as characterized by a preeminent clonal structure. {N}evertheless, with the development of elaborate culture experiments, population genetics and evolutionary and population genomics, several studies suggested that most of these pathogens were also characterized by constitutive genetic recombination events. {I}n this opinion, we focused on {L}eishmania parasites, pathogens responsible of leishmaniases, a major public health issue. {W}e first discuss the evolutionary advantages of a mixed mating reproductive strategy, then we review the evidence of genetic exchange, and finally we detail available tools to detect naturally occurring genetic recombination in {L}eishmania parasites and more generally in protozoan parasites.},
  keywords = {{L}eishmania ; {G}enetic exchange ; {R}eproductive strategies},
  booktitle = {},
  journal = {{I}nfection {G}enetics and {E}volution},
  volume = {50},
  numero = {},
  pages = {128--132},
  ISSN = {1567-1348},
  year = {2017},
  DOI = {10.1016/j.meegid.2016.10.013},
  URL = {https://www.documentation.ird.fr/hor/fdi:010069524},
}