@article{fdi:010069482,
  title = {{V}itamin {A} in pediatrics : an update from the {N}utrition {C}ommittee of the {F}rench {S}ociety of {P}ediatrics},
  author = {{V}idailhet, {M}. and {R}ieu, {D}. and {F}eillet, {F}. and {B}ocquet, {A}. and {C}houraqui, {J}. {P}. and {D}armaun, {D}. and {D}upont, {C}. and {F}relut, {M}. {L}. and {G}irardet, {J}. {P}. and {H}ankard, {R}. and {R}oze, {J}. {C}. and {S}imeoni, {U}. and {T}urck, {D}. and {B}riend, {A}ndr{\'e}},
  editor = {},
  language = {{ENG}},
  abstract = {{V}itamin {A} (retinol) fulfills multiple functions in vision, cell growth and differentiation, embryogenesis, the maintenance of epithelial harriers and immunity. {V} large number of enzymes, binding proteins and receptors facilitate its intestinal absorption, hepatic storage, secretion, and distribution to target cells. {I}n addition to the preformed retinol of animal origin, some fruits and vegetables are rich in carotenoids with provitamin {A} precursors such as beta-carotene: 6 mu g of beta-carotene corresponds to 1 mu g retinol equivalent ({RE}). {C}arotenoids never cause hypervitaminosis {A}. {D}etermination of liver retinol concentration, the most reliable marker of vitamin {A} status, cannot be used in practice. {D}espite its lack of sensitivity and specificity, the concentration of retinol in blood is used to assess vitamin {A} status. {A} blood vitamin {A} concentration below 0.70 mu mol/{L} (200 mu g/{L}) indicates insufficient intake. {L}evels above 1.05 mu mol/{L} (300 mu g/{L}) indicate an adequate vitamin {A} status. {T}he recommended dietary intake increases from 250 mu g {RE}/day between 7 and 36 months of age to 750 mu g {RE}/day between 15 and 17 years of age, which is usually adequate in industrialized countries. {H}owever, intakes often exceed the recommended intake, or even the upper limit (600 mu g/day), in some non-breastfed infants. {T}he new {E}uropean regulation on infant and follow-on formulas (2015) will likely limit this excessive intake. {I}n some developing countries, vitamin {A} deficiency is one of the main causes of blindness and remains a major public health problem. {T}he impact of vitamin {A} deficiency on mortality was not confirmed by the most recent studies. {P}eriodic supplementation with high doses of vitamin {A} is currently questioned and food diversification, fortification or low-dose regular supplementation seem preferable.},
  keywords = {{FRANCE}},
  booktitle = {},
  journal = {{A}rchives de {P}{\'e}diatrie},
  volume = {24},
  numero = {3},
  pages = {288--297},
  ISSN = {0929-693{X}},
  year = {2017},
  DOI = {10.1016/j.arcped.2016.11.021},
  URL = {https://www.documentation.ird.fr/hor/fdi:010069482},
}