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Vieira C., Gaubert J., De Clerck O., Payri Claude, Culioli G., Thomas O. P. (2017). Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae). Phytochemistry Reviews, 16 (1), 1-17. ISSN 1568-7767

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Lien direct chez l'éditeur doi:10.1007/s11101-015-9445-x

Titre
Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)
Année de publication2017
Type de documentArticle référencé dans le Web of Science WOS:000397921500001
AuteursVieira C., Gaubert J., De Clerck O., Payri Claude, Culioli G., Thomas O. P.
SourcePhytochemistry Reviews, 2017, 16 (1), p. 1-17. ISSN 1568-7767
RésuméAlthough Lobophora belongs to a marine algal family (Dictyotaceae) that produces a large array of secondary metabolites, it has received little attention compared to other genera, such as Dictyota, in terms of natural compounds isolation and characterization. However, metabolites produced by Lobophora species have been found to exhibit a wide array of bioactivities including pharmacological (e.g. antibacterial, antiviral, antioxidant, antitumoral), pesticidal, and ecological. This review aims to report the state-of-the-art of the natural products isolated from Lobophora species (Dictyotales, Phaeophyceae) and their associated bioactivities. All bioactivities documented in the literature are reported, therefore including studies for which pure active substances were described, as well as studies limited to extracts or fractions. From the early 1980s until today, 49 scientific works have been published on Lobophora chemistry and bioactivity, among which 40 have reported bioactivities. Only six studies, however, have identified, characterized and tested no less than 23 bioactive pure compounds (three C-21 polyunsaturated alcohols, three fatty-acids, a macrolactone, 11 polyketides, a few sulfated polysaccharides, three sulfolipids, a tocopherol derivative). The present review intends to raise awareness of chemists and biologists given the recent significant taxonomic progress of this brown algal genus, which holds a promising plethora of natural products yet to be discovered with ecological and pharmacological properties.
Plan de classementSubstances naturelles [035]
LocalisationFonds IRD [F B010069445]
Identifiant IRDfdi:010069445
Lien permanenthttp://www.documentation.ird.fr/hor/fdi:010069445

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