@article{fdi:010069427,
  title = {{F}ormula-feeding of {HIV}-exposed uninfected {A}frican children is associated with faster growth in length during the first 6 months of life in the {K}esho {B}ora {S}tudy},
  author = {{B}ork, {K}irsten and {C}ames, {C}{\'e}cile and {N}ewell, {M}. {L}. and {R}ead, {J}. {S}. and {A}yassou, {K}. and {M}usyoka, {F}. and {M}batia, {G}. and {C}ournil, {A}mandine and {K}esho {B}ora {S}tudy {G}roup},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {E}arly feeding patternsmay affect the growth of {HIV}-exposed children and thus their subsequent health and cognition. {O}bjective: {W}e assessed the association of infant feeding ({IF}) mode with length-for-age z score ({LAZ}) and stunting fromage 2 d to 18 mo in {HIV}-exposed {A}frican childrenwithin a controlled randomized trial, which evaluated triple antiretrovirals initiated during pregnancy and continued for 6 mo postpartum to prevent {HIV} transmission. {M}ethods: {HIV}-infected pregnant women with {CD}4 + counts of 200-500 cells/mm(3) from {B}urkina {F}aso, {K}enya, and {S}outh {A}frica were advised to exclusively breastfeed for up to 6 mo or to formula-feed from birth. {F}actors associated with {LAZ} were investigated in all uninfected children by using mixed-effects linear models; those associated with stunting ({LAZ} < 22) at 6 or 12 mo were assessed in multiple logistic regression after exclusion of children stunted at age 2 d. {I}ndependent variables were {IF} mode: formula feeding ({FF}), exclusive breastfeeding ({EBF}) < 3 mo, or {EBF} $ 3 mo (reference); sex; trial arm; maternal characteristics; and site. {R}esults: {A}mong 728 children, {FF} was associated with a greater increase in {LAZ} from 2 d to 6 mo (+ 0.07 z score/mo, {P} < 0.001). {B}etween 6 and 18 mo, {FF} and {EBF} < 3mowere both associated with greatermean {LAZ} than was {EBF}$ 3mo (+ 0.52z scores and + 0.43 z scores, respectively, {P} < 0.001). {A}mong children not stunted at 2 d, {FF} was independently associatedwith a reduced risk of stunting at 6mo ({OR}: 0.24; 95% {CI}: 0.07, 0.81; {P} = 0.021), whereas {EBF} < 3 mo was not ({OR}: 0.49; 95% {CI}: 0.22, 1.10; {P}= 0.09). {C}onclusions: {I}n this observational study of {HIV}-exposed uninfected infants, growth in length in the first 6mo of lifewas faster in formula-fed infants than in exclusively breastfed infants. {T}he plausibility of},
  keywords = {{A}frica ; breastfeeding ; {HIV} infection ; infant growth ; stunting ; {BURKINA} {FASO} ; {KENYA} ; {AFRIQUE} {DU} {SUD}},
  booktitle = {},
  journal = {{J}ournal of {N}utrition},
  volume = {147},
  numero = {3},
  pages = {453--461},
  ISSN = {0022-3166},
  year = {2017},
  DOI = {10.3945/jn.116.242339},
  URL = {https://www.documentation.ird.fr/hor/fdi:010069427},
}