@article{fdi:010069367, title = {{P}otential of {A}edes aegypti and {A}edes albopictus populations in the {C}entral {A}frican {R}epublic to transmit enzootic chikungunya virus strains}, author = {{N}goagouni, {C}. and {K}amgang, {B}. and {K}azanji, {M}. and {P}aupy, {C}hristophe and {N}akoune, {E}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {M}ajor chikungunya outbreaks have affected several {C}entral {A}frican countries during the past decade. {T}he chikungunya virus ({CHIKV}) was isolated from humans and sylvan mosquitoes in the {C}entral {A}frican {R}epublic ({CAR}) during the 1970 and 1980s but has not been found recently, despite the presence of {A}edes albopictus since 2010. {T}he risk of a massive chikungunya epidemic is therefore potentially high, as the human populations are immunologically naive and because of the presence of the mosquito vector. {I}n order to estimate the risk of a large outbreak, we assessed the vector competence of local {A}e. aegypti and {A}e. albopictus populations for ancient local strains of {CHIKV} in {CAR}. {M}osquitoes were orally infected with the virus, and its presence in mosquito saliva was analysed 7 and 14 days post-infection (dpi) by quantitative reverse transcriptase polymerase chain reaction. {R}esults: {T}he two species had similar infection rates at 7 and 14 days, and the dissemination rate of both vectors was >= 80% at 14 dpi. {O}nly females followed up to 14 dpi had {CHKV} in their saliva. {C}onclusion: {T}hese results confirm the risk of transmission of enzootic {CHIKV} by anthropophilic vectors such as {A}e. aegypti and {A}e. albopictus.}, keywords = {{C}hikungunya virus ; {E}nzootic strain ; {V}ector competence ; {A}edes aegypti ; {A}edes albopictus ; {C}entral {A}frican {R}epublic ; {CENTRAFRIQUE}}, booktitle = {}, journal = {{P}arasites and {V}ectors}, volume = {10}, numero = {}, pages = {art. 164 [5 p.]}, ISSN = {1756-3305}, year = {2017}, DOI = {10.1186/s13071-017-2101-0}, URL = {https://www.documentation.ird.fr/hor/fdi:010069367}, }