%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Schuster, D.
%A Rickmeyer, J.
%A Gajdiss, M.
%A Thye, T.
%A Lorenzen, S.
%A Reif, M.
%A Josten, M.
%A Szekat, C.
%A Melo, L. D. R.
%A Schmithausen, R. M.
%A Liégeois, Florian
%A Sahl, H. G.
%A Gonzalez, J. P.
%A Nagel, M.
%A Bierbaum, G.
%T Differentiation of Staphylococcus argenteus (formerly : Staphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape
%D 2017
%L fdi:010069293
%G ENG
%J International Journal of Medical Microbiology
%@ 1438-4221
%K Staphylococcus argenteus ; Staphylococcus aureus ; Staphylococcus schweitzeri ; Gorilla gorilla ssp gorilla ; MALDI-TOF MS ; Virulence determinants
%K GABON
%M ISI:000394073600007
%N 1
%P 57-63
%R 10.1016/j.ijmm.2016.11.003
%U https://www.documentation.ird.fr/hor/fdi:010069293
%> https://www.documentation.ird.fr/intranet/publi/2017/03/010069293.pdf
%V 307
%W Horizon (IRD)
%X The species Staphylococcus argenteus was separated recently from Staphylococcus aureus (Tong S.Y., F. Schaumburg, M.J. Ellington, J. Corander, B. Pichon, F. Leendertz, S.D. Bentley, J. Parkhill, D.C. Holt, G. Peters, and P.M. Giffard, 2015). The objective of this work was to characterise the genome of a non-human S. argenteus strain, which had been isolated from the faeces of a wild-living western lowland gorilla in Gabon, and analyse the spectrum of this species in matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). The full genome sequence revealed a scarcity of virulence genes and absence of resistance genes, indicating a decreased virulence potential compared to S. aureus and the human methicillin-resistant S. argenteus isolate MSHR1132(T). Spectra obtained by MALDI-TOF MS and the analysis of available sequences in the genome databases identified several MALDI-TOF MS signals that clearly differentiate S. argenteus, the closely related Staphylococcus schweitzeri and S. aureus. In conclusion, in the absence of biochemical tests that identify the three species, mass spectrometry should be employed as method of choice.
%$ 084 ; 080