@article{fdi:010068910,
  title = {{S}erological evidence of contrasted exposure to arboviral infections between islands of the {U}nion of {C}omoros ({I}ndian {O}cean)},
  author = {{D}ellagi, {K}oussay and {S}alez, {N}. and {M}aquart, {M}. and {L}arrieu, {S}. and {Y}ssouf, {A}. and {S}ilai, {R}. and {L}eparc-{G}offart, {I}. and {T}ortosa, {P}. and de {L}amballerie, {X}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A} cross sectional serological survey of arboviral infections in humans was conducted on the three islands of the {U}nion of {C}omoros, {I}ndian {O}cean, in order to test a previously suggested contrasted exposure of the three neighboring islands to arthropod-borne epidemics. {F}our hundred human sera were collected on {N}gazidja ({G}rande {C}omore), {M}wali ({M}oheli) and {N}dzouani ({A}njouan), and were tested by {ELISA} for {I}g{M} and/or {I}g{G} antibodies to {D}engue ({DENV}), {C}hikungunya ({CHIKV}), {R}ift {V}alley fever ({RVFV}), {W}est {N}ile ({WNV}), {T}ick borne encephalitis ({TBEV}) and {Y}ellow fever ({YFV}) viruses and for neutralizing antibodies to {DENV} serotypes 1-4. {V}ery few sera were positive for {I}g{M} antibodies to the tested viruses indicating that the sero-survey was performed during an inter epidemic phase for the investigated arbovirus infections, except for {RVF} which showed evidence of recent infections on all three islands. {I}g{G} reactivity with at least one arbovirus was observed in almost 85% of tested sera, with seropositivity rates increasing with age, indicative of an intense and long lasting exposure of the {C}omorian population to arboviral risk. {I}nterestingly, the positivity rates for {I}g{G} antibodies to {DENV} and {CHIKV} were significantly higher on {N}gazidja, confirming the previously suggested prominent exposure of this island to these arboviruses, while serological traces of {WNV} infection were detected most frequently on {M}wali suggesting some transmission specificities associated with this island only. {T}he study provides the first evidence for circulation of {RVFV} in human populations from the {U}nion of {C}omoros and further suggests that the virus is currently circulating on the three islands in an inconspicuous manner. {T}his study supports contrasted exposure of the islands of the {C}omoros archipelago to arboviral infections. {T}he observation is discussed in terms of ecological factors that may affect the abundance and distribution of vector populations on the three islands as well as concurring anthropogenic factors that may impact arbovirus transmission in this diverse island ecosystem.},
  keywords = {{COMORES} ; {OCEAN} {INDIEN}},
  booktitle = {},
  journal = {{P}los {N}eglected {T}ropical {D}iseases},
  volume = {10},
  numero = {12},
  pages = {art. e0004840 [14 ]},
  ISSN = {1935-2735},
  year = {2016},
  DOI = {10.1371/journal.pntd.0004840},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068910},
}