@article{fdi:010068900,
  title = {{T}he host specificity of ape malaria parasites can be broken in confined environments},
  author = {{N}goubangoye, {B}. and {B}oundenga, {L}. and {A}rnathau, {C}. and {M}ombo, {I}. {M}. and {D}urand, {P}. and {T}soumbou, {T}. {A}. and {O}toro, {B}. {V}. and {S}ana, {R}. and {O}kouga, {A}. {P}. and {M}oukodoum, {N}. and {W}illaume, {E}. and {H}erbert, {A}. and {F}ouchet, {D}. and {R}ougeron, {V}. and {B}a, {C}. {T}. and {O}llomo, {B}. and {P}aupy, {C}hristophe and {L}eroy, {E}ric and {R}enaud, {F}. and {P}ontier, {D}. and {P}rugnolle, {F}ranck},
  editor = {},
  language = {{ENG}},
  abstract = {{R}ecent studies have revealed a large diversity of {P}lasmodium spp. among {A}frican great apes. {S}ome of these species are related to {P}lasmodium falciparum, the most virulent agent of human malaria (subgenus {L}averania), and others to {P}lasmodium ovale, {P}lasmodium malariae and {P}lasmodium vivax (subgenus {P}lasmodium), three other human malaria agents. {L}averania parasites exhibit strict host specificity in their natural environment. {P}lasmodium reichenowi, {P}lasmodium billcollinsi, {P}lasmodium billbrayi and {P}lasmodium gaboni infect only chimpanzees, while {P}lasmodium praefalciparum, {P}lasmodium blacklocki and {P}lasmodium adleri are restricted to gorillas and {P}lasmodium falciparum is pandemic in humans. {T}his host specificity may be due to genetic and/or environmental factors. {I}nfrastructures hosting captive primates, such as sanctuaries and health centres, usually concentrate different primate species, thus favouring pathogen exchanges. {U}sing molecular tools, we analysed blood samples from captive non-human primates living in {G}abon to evaluate the risk of {P}lasmodium spp. transfers between host species. {W}e also included blood samples from workers taking care of primates to assess whether primate-human parasite transfers occurred. {W}e detected four transfers of {P}lasmodium from gorillas towards chimpanzees, one from chimpanzees to gorillas, three from humans towards chimpanzees and one from humans to mandrills. {N}o simian {P}lasmodium was found in the blood samples from humans working with primates. {T}hese findings demonstrate that the genetic barrier that determines the apparent host specificity of {L}averania is not completely impermeable and that parasite exchanges between gorillas and chimpanzees are possible in confined environments.},
  keywords = {{H}uman ; {G}reat apes ; {L}averania subgenus ; {H}ost specificity ; {C}ross-species transfers ; {S}anctuaries ; {GABON}},
  booktitle = {},
  journal = {{I}nternational {J}ournal for {P}arasitology},
  volume = {46},
  numero = {11},
  pages = {737--744},
  ISSN = {0020-7519},
  year = {2016},
  DOI = {10.1016/j.ijpara.2016.06.004},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068900},
}