@article{fdi:010068851, title = {{S}evere human illness caused by {R}ift {V}alley fever virus in {M}auritania, 2015}, author = {{B}oushab, {B}. {M}. and {F}all-{M}alick, {F}. {Z}. and {B}aba, {S}ewo and {S}alem, {M}. {L}. {O}. and {B}elizaire, {M}. {R}. {D}. and {L}edib, {H}. and {A}hmed, {M}mob and {B}asco, {L}eonardo and {B}a, {H}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground. {R}ift {V}alley {F}ever epizootics are characterized by numerous abortions and mortality among young animals. {I}n humans, the illness is usually characterized by a mild self-limited febrile illness, which could progress to more serious complications. {O}bjectives. {T}he aim of the present prospective study was to describe severe clinical signs and symptoms of {R}ift {V}alley {F}ever in southern {M}auritania. {P}atients and methods. {S}uspected cases were enrolled in {K}iffa ({A}ssaba) and {A}leg ({B}rakna) {H}ospital {C}enters from {S}eptember 1 to {N}ovember 7, 2015, based on the presence of fever, hemorrhagic or meningoencephalitic syndromes, and probable contact with sick animals. {S}uspected cases were confirmed by enzyme-linked immunosorbent assay ({ELISA}) and reverse transcriptase-polymerase chain reaction ({RT}-{PCR}). {R}esults. {T}here were thirty-one confirmed cases. {T}he sex ratio {M}/{F} and the average age were 2.9 and 25 years old [range, 4-70 years old], respectively. {M}osquito bites, direct contact with aborted or dead animals, and frequent ingestion of milk from these animals were risk factors observed in all patients. {H}emorrhagic and neurological manifestations were observed in 81% and 13% of cases, respectively. {T}he results of laboratory analysis showed high levels of transaminases, creatinine, and urea associated with thrombocytopenia, anemia, and leukopenia. {A}ll patients who died (42%) had a hemorrhagic syndrome and 3 of them had a neurological complication. {A}mong the cured patients, none had neurologic sequelae. {C}onclusion. {T}he hemorrhagic form was the most common clinical manifestation of {RVF} found in southern {M}auritania and was responsible for a high mortality rate. {O}ur results justify the implementation of a continuous epidemiological surveillance.}, keywords = {{A}ssaba ; {B}rakna ; {M}auritania ; {R}ift valley fever ; severe human illness ; {MAURITANIE}}, booktitle = {}, journal = {{O}pen {F}orum {I}nfectious {D}iseases}, volume = {3}, numero = {4}, pages = {}, ISSN = {2328-8957}, year = {2016}, DOI = {10.1093/ofid/ofw200}, URL = {https://www.documentation.ird.fr/hor/fdi:010068851}, }