@article{fdi:010068821,
  title = {{A}ntibiotic pollution in the {K}atari subcatchment of the {T}iticaca {L}ake : major transformation products and occurrence of resistance genes},
  author = {{A}rchundia, {D}. and {D}uwig, {C}{\'e}line and {L}ehembre, {F}. and {C}hiron, {S}erge and {M}orel, {M}. {C}. and {P}rado, {B}. and {B}ourdat-{D}eschamps, {M}. and {V}ince, {E}. and {A}viles, {G}. {F}. and {M}artins, {J}. {M}. {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}n increasing number of studies pointed out the ubiquitous presence of medical residues in surface and ground water as well as in soil compartments. {N}ot only antibiotics can be found in the environment but also their transformation products about which little information is generally available. {T}he development of bacterial resistance to antibiotics is particularly worrying as it can lead to sanitary and health problems. {S}tudies about the dissemination of antibiotics and associated resistances in the {B}olivian {A}ltiplano are scarce. {W}e provide baseline information on the occurrence of {S}ulfamethoxazole ({SMX}) and {T}rimethoprim ({TMP}) antibiotics as well as on the most common human {SMX} transformation products ({TP}) and on the occurrence of sulfonamide resistance genes. {T}he studied water and soil compartments presented high levels of antibiotic pollution. {T}his situation was shown to be mainly linked with uncontrolled discharges of treated and untreated wastewaters, resulting on the presence of antibiotics in the {T}iticaca {L}ake. {SMXTP}s were detected in surface waters and on soil sampled next to the wastewater treatment plant ({WWTP}). {SMX} resistance genes sull and sulll were widely detected in the basin hydrological network, even in areas unpolluted with antibiotics. {M}echanisms of co-selection of antibiotic-and metal-resistance may be involved in the prevalence of {ARG}'s in pristine areas with no anthropogenic activity and free of antibiotic pollution.},
  keywords = {{W}ater ; {S}oil ; {S}ulfamethoxazole ; {T}rimethoprim ; {A}ntibiotic resistance genes ; ({ARG}s) ; {A}ltiplano ; {BOLIVIE} ; {ALTIPLANO}},
  booktitle = {},
  journal = {{S}cience of the {T}otal {E}nvironment},
  volume = {576},
  numero = {},
  pages = {671--682},
  ISSN = {0048-9697},
  year = {2017},
  DOI = {10.1016/j.scitotenv.2016.10.129},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068821},
}