@article{fdi:010068705,
  title = {{P}renatal iron deficiency, neonatal ferritin, and infant cognitive function},
  author = {{M}ireku, {M}. {O}. and {D}avidson, {L}. {L}. and {B}oivin, {M}. {J}. and {Z}oumenou, {R}. and {M}assougbodji, {A}. and {C}ot, {M}ichel and {B}odeau-{L}ivinec, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{OBJECTIVE}: {T}o investigate the impact of prenatal maternal iron deficiency ({ID}) on cord blood serum ferritin ({CBSF}) concentration and infant cognitive and motor development. {METHODS}: {O}ur prospective cohort study included 636 mother-singleton child pairs from 828 eligible pregnant women who were enrolled during their first antenatal care ({ANC}) visit in {A}llada, {B}enin, into a clinical trial comparing the efficacy of mefloquine and sulfadoxine-pyrimethamine. {V}enous blood samples of women were assessed for ferritin and hemoglobin concentrations at the first and second {ANC} visits (occurring at least 1-month apart) and at delivery. {W}omen were prescribed daily iron and folic acid supplements throughout pregnancy. {H}ematologic examinations were repeated for cord blood at birth. {A}t age 1 year, cognitive and motor functions of children were assessed by using the {M}ullen {S}cales of {E}arly {L}earning. {RESULTS}: {T}he prevalence of prenatal {ID} at first and second {ANC} visits, and at delivery was 30.5%, 34.0%, and 28.4%, respectively. {CBSF} concentrations were similar between {ID} and non-{ID} pregnant women. {N}either prenatal {ID} nor {CBSF} concentration was associated with poor cognitive or gross motor function of children at age 1 year. {CBSF} concentrations were lower among mothers who had {ID} anemia ({IDA}) at delivery compared with non-{IDA} pregnant women (adjusted mean difference: -0.2 [95% confidence interval: -0.4 to -0.0]). {CONCLUSIONS}: {I}n a malaria-endemic region, {ID} in pregnancy in the context of iron supplementation is neither associated with {CBSF} concentration nor with infant cognitive and motor development. {P}renatal {IDA} around the time of delivery is associated with lower {CBSF} concentrations.},
  keywords = {{BENIN}},
  booktitle = {},
  journal = {{P}ediatrics},
  volume = {138},
  numero = {6},
  pages = {e20161319 [11 p.]},
  ISSN = {0031-4005},
  year = {2016},
  DOI = {10.1542/peds.2016-1319},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068705},
}