@article{fdi:010068107,
  title = {{P}revalence of malaria in pregnancy in southern {L}aos : a cross-sectional survey},
  author = {{B}riand, {V}al{\'e}rie and {L}e {H}esran, {J}ean-{Y}ves and {M}ayxay, {M}. and {N}ewton, {P}. {N}. and {B}ertin, {G}wladys and {H}ouze, {S}. and {K}eomany, {S}. and {I}nthavong, {Y}. and {V}annavong, {N}. and {C}hindavongsa, {K}. and {H}ongvanthong, {B}. and {F}ievet, {N}adine},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}here are no data on the burden of malaria in pregnancy ({M}i{P}) in {L}aos, where malaria still remains prevalent in the south. {M}ethods: {T}wo cross-sectional surveys were conducted in 2014 to assess the prevalence of {M}i{P} in {V}api {D}istrict, {S}alavan {P}rovince, southern {L}aos: the first consisted of screening 204 pregnant women during pregnancies [mean (95 % {CI}) gestational age: 23 (22-25) weeks] living in 30 randomly selected villages in {V}api {D}istrict; the second was conducted among 331 pregnant women, who delivered during the study period in {V}api and {T}oumlane {D}istrict {H}ospitals and in {S}alavan {P}rovincial {H}ospital. {P}eripheral and placental malaria was detected using rapid diagnostic tests ({RDT}), thick blood smears ({TBS}) and real-time quantitative polymerase chain reactions ({RT}-q{PCR}). {F}actors associated with low birth weight ({LBW}) and maternal anaemia were assessed. {R}esults: {I}n the villages, 12/204 women (5.9 %; 95 % {CI} 3.1-10.0) were infected with malaria as determined by {RT}-q{PCR}: 11 were {P}lasmodium vivax infections and 1 was mixed {P}lasmodium vivax/{P}lasmodium falciparum infection, among which 9 were sub-microscopic (as not detected by {TBS}). {H}istory of malaria during current pregnancy tended to be associated with a higher risk of {M}i{P} (a{IRR} 3.05; 95 % {CI} 0.94-9.88). {A}t delivery, two {P}lasmodium falciparum submicroscopic infections (one peripheral and one placental) were detected (4.5 %; 0.6-15.5) in {V}api {D}istrict. {I}n both surveys, all infected women stated they had slept under a bed net the night before the survey, and 86 % went to the forest for food-finding 1 week before the survey in median. {T}he majority of infections (94 %) were asymptomatic and half of them were associated with anaemia. {O}verall, 24 % of women had {LBW} newborns. {F}actors associated with a higher risk of {LBW} were tobacco use (a{IRR} 2.43; 95 % {CI} 1.64-3.60) and pre-term delivery (a{IRR} 3.17; 95 % {CI} 2.19-4.57). {F}actors associated with a higher risk of maternal anaemia were no iron supplementation during pregnancy, {L}ao {T}heung ethnicity and place of living. {C}onclusions: {T}he prevalence of {M}i{P} in this population was noticeable. {M}ost infections were asymptomatic and submicroscopic vivax malaria, which raises the question of reliability of recommended national strategies for the screening and prevention of {M}i{P} in {L}aos.},
  keywords = {{M}alaria ; {P}regnancy ; {L}ow birth weight ; {E}pidemiology ; {M}olecular biology ; {L}aos ; {LAOS}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {15},
  numero = {},
  pages = {art. 436 [11 p.]},
  ISSN = {1475-2875},
  year = {2016},
  DOI = {10.1186/s12936-016-1492-2},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068107},
}