@article{fdi:010067756,
  title = {{Y}oung adolescent girls are at high risk for adverse pregnancy outcomes in sub-{S}aharan {A}frica : an observational multicountry study},
  author = {{M}ombo-{N}goma, {G}. and {M}ackanga, {J}. {R}. and {G}onzalez, {R}. and {O}uedraogo, {S}. and {K}akolwa, {M}. {A}. and {M}anego, {R}. {Z}. and {B}asra, {A}. and {R}uperez, {M}. and {C}ot, {M}ichel and {K}abanywany, {A}. {M}. and {M}atsiegui, {P}. {B}. and {A}gnandji, {S}. {T}. and {V}ala, {A}. and {M}assougbodji, {A}. and {A}bdulla, {S}. and {A}degnika, {A}. {A}. and {S}evene, {E}. and {M}acete, {E}. and {Y}azdanbakhsh, {M}. and {K}remsner, {P}. {G}. and {A}ponte, {J}. {J}. and {M}enendez, {C}. and {R}amharter, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjectives {O}ne of {A}frica's most important challenges is to improve maternal and neonatal health. {T}he identification of groups at highest risk for adverse pregnancy outcomes is important for developing and implementing targeted prevention programmes. {T}his study assessed whether young adolescent girls constitute a group at increased risk for adverse birth outcomes among pregnant women in sub-{S}aharan {A}frica. {S}etting {D}ata were collected prospectively as part of a large randomised controlled clinical trial evaluating intermittent preventive treatment of malaria in pregnancy ({NCT}00811421{C}linical {T}rials.gov), conducted between {S}eptember 2009 and {D}ecember 2013 in {B}enin, {G}abon, {M}ozambique and {T}anzania. {P}articipants {O}f 4749 participants, pregnancy outcomes were collected for 4388 deliveries with 4183 live births including 83 multiple gestations. {O}f 4100 mothers with a singleton live birth delivery, 24% (975/4100) were adolescents (19years of age) and 6% (248/4100) were aged 16years. {P}rimary and secondary outcome measures {P}rimary outcomes of this predefined analysis were preterm delivery and low birth weight. {R}esults {T}he overall prevalence of low birthweight infants and preterm delivery was 10% (371/3851) and 4% (159/3862), respectively. {M}others aged 16years showed higher risk for the delivery of a low birthweight infant ({OR}: 1.96; 95% {CI} 1.35 to 2.83). {S}imilarly, preterm delivery was associated with young maternal age (16years; {OR}: 2.62; 95% {CI} 1.59 to 4.30). {I}n a subanalysis restricted to primiparous women: preterm delivery, {OR} 4.28; 95% {CI} 2.05 to 8.93; low birth weight, {OR}: 1.29; 95% {CI} 0.82 to 2.01. {C}onclusions {Y}oung maternal age increases the risk for adverse pregnancy outcomes and it is a stronger predictor for low birth weight and preterm delivery than other established risk factors in sub-{S}aharan {A}frica. {T}his finding highlights the need to improve adolescent reproductive health in sub-{S}aharan {A}frica. {T}rial registration number {NCT}00811421; {P}ost-results.},
  keywords = {adolescent pregnancy ; sub-{S}aharan {A}frica ; low birth weight ; preterm birth ; {BENIN} ; {GABON} ; {MOZAMBIQUE} ; {TANZANIE} ; {AFRIQUE} {SUBSAHARIENNE}},
  booktitle = {},
  journal = {{BMJ} {O}pen},
  volume = {6},
  numero = {6},
  pages = {e011783 [8 p.]},
  ISSN = {2044-6055},
  year = {2016},
  DOI = {10.1136/bmjopen-2016-011783},
  URL = {https://www.documentation.ird.fr/hor/fdi:010067756},
}