@article{fdi:010067689,
  title = {{D}eciphering the adaptation strategies of {D}esulfovibrio piezophilus to hydrostatic pressure through metabolic and transcriptional analyses},
  author = {{A}mrani, {A}. and van {H}elden, {J}. and {B}ergon, {A}. and {A}ouane, {A}. and {B}en {H}ania, {W}ajdi and {T}amburini, {C}. and {L}oriod, {B}. and {I}mbert, {J}. and {O}llivier, {B}ernard and {P}radel, {N}athalie and {D}olla, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{D}esulfovibrio piezophilus strain {C}1{TLV}30({T}) is a mesophilic piezophilic sulfate-reducer isolated from {W}ood {F}alls at 1700 m depth in the {M}editerranean {S}ea. {I}n this study, we analysed the effect of the hydrostatic pressure on this deep-sea living bacterium at the physiologic and transcriptomic levels. {O}ur results showed that lactate oxidation and energy metabolism were affected by the hydrostatic pressure. {E}specially, acetyl-{C}o{A} oxidation pathway and energy conservation through hydrogen and formate recycling would be more important when the hydrostatic pressure is above (26 {MP}a) than below (0.1 {MP}a) the optimal one (10 {MP}a). {T}his work underlines also the role of the amino acid glutamate as a piezolyte for the {D}esulfovibrio genus. {T}he transcriptomic analysis revealed 146 differentially expressed genes emphasizing energy production and conversion, amino acid transport and metabolism and cell motility and signal transduction mechanisms as hydrostatic pressure responding processes. {T}his dataset allowed us to identify a sequence motif upstream of a subset of differentially expressed genes as putative pressure-dependent regulatory element.},
  keywords = {{MEDITERRANEE}},
  booktitle = {},
  journal = {{E}nvironmental {M}icrobiology {R}eports},
  volume = {8},
  numero = {4},
  pages = {520--526},
  ISSN = {1758-2229},
  year = {2016},
  DOI = {10.1111/1758-2229.12427},
  URL = {https://www.documentation.ird.fr/hor/fdi:010067689},
}