@article{fdi:010067624,
  title = {{T}he high prevalence of anemia in {C}ambodian children and women cannot be satisfactorily explained by nutritional deficiencies or hemoglobin disorders},
  author = {{W}ieringa, {F}ranck and {D}ahl, {M}. and {C}hamnan, {C}. and {P}oirot, {E}. and {K}uong, {K}. and {S}ophonneary, {P}. and {S}inuon, {M}. and {G}reffeuille, {V}al{\'e}rie and {H}ong, {R}. and {B}erger, {J}acques and {D}ijkhuizen, {M}. {A}. and {L}aillou, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {A}nemia is highly prevalent in {C}ambodian women and children, but data on causes of anemia are scarce. {W}e performed a national micronutrient survey in children and women that was linked to the {C}ambodian {D}emographic {H}ealth {S}urvey 2014 ({CDHS}-2014) to assess the prevalence of micronutrient deficiency, hemoglobin disorders and intestinal parasite infection. {M}ethods: {O}ne-sixth of households from the {CDHS}-2014 were selected for a follow-up visit for the micronutrient survey. {H}ouseholds were visited from two weeks to two months after the {CDHS}-2014 visit. {D}ata on micronutrient status were available for 1512 subjects (792 children and 720 women). {R}esults: {A}nemia was found in 43% of the women and 53% of the children. {H}emoglobin disorders affected >50% of the population, with {H}emoglobin-{E} the most prevalent disorder. {D}eficiencies of iron (ferritin < 15 g/{L}), vitamin {A} (retinol-binding-protein ({RBP}) < 0.70 mol/{L}) or vitamin {B}12 (<150 pmol/{L}) were not prevalent in the women (<5% for all), whereas 17.8% of the women had low concentrations of folic acid (<10 nmol/{L}). {I}n the children, the prevalence of iron, vitamin {A}, vitamin {B}12 or folic acid deficiency was <10%. {Z}inc deficiency, hookworm infection and hemoglobinopathy were significantly associated with anemia in children, whereas in the women none of the factors was significantly associated with anemia. {I}ron deficiency anemia ({IDA}) was more prevalent in children <2 years, but in older children and women, the prevalence of {IDA} was <5%. {T}he most prevalent, preventable causes of anemia were hookworm infection and zinc and folic acid deficiency. {O}ver 40% of the anemia was not caused by nutritional factors. {C}onclusion: {T}he very high prevalence of anemia in {C}ambodian women and children cannot be explained solely by micronutrient deficiencies and hemoglobin disorders. {M}icronutrient interventions to improve anemia prevalence are likely to have limited impact in the {C}ambodian setting. {T}he focus of current interventions to reduce the high prevalence of anemia in children and women should be broadened to include zinc and folic acid as well as effective anti-hookworm measures.},
  keywords = {anemia ; iron ; vitamin {A} ; folic acid ; vitamin {B}12 ; zinc ; hemoglobin ; disorders ; children ; women of reproductive age ; {C}ambodia ; {CAMBODGE}},
  booktitle = {},
  journal = {{N}utrients},
  volume = {8},
  numero = {6},
  pages = {art. 348 [12 p.]},
  ISSN = {2072-6643},
  year = {2016},
  DOI = {10.3390/nu8060348},
  URL = {https://www.documentation.ird.fr/hor/fdi:010067624},
}