@article{fdi:010067219, title = {{M}odeling and predicting the long-term effects of various strategies and objectives of varicella-zoster vaccination campaigns}, author = {{R}iche, {B}. and {B}ricout, {H}. and {K}ürzinger, {M}.{L}. and {R}oche, {S}. and {I}waz, {J}. and {E}tard, {J}ean-{F}ran{\c{c}}ois and {E}cochard, {R}.}, editor = {}, language = {{ENG}}, abstract = {{BACKGROUND}: {S}usceptible, exposed, infected, and recovered ({SEIR}) models are increasingly developed and used, but their simplicity contrasts with the wide variety of scenarios before launching vaccination campaigns. {METHODS}: {W}e investigated the effects of some model-building choices (targets, pace, coverage rate) on the results of {SEIR} models in the case of vaccination against varicella and herpes zoster. {RESULTS}: {T}he analysis demonstrated the need for a progressive unvaccinated to vaccinated transition and a dynamic system-equilibrium before vaccination onset. {W}hen several doses are considered, new compartments are needed to account for vaccination histories. {F}or varicella, the delay to reach the expected coverage rate and the pace until reaching this rate have significant impacts, especially on the short-term incidence. {T}he impact of vaccination through herd immunity should be systematically investigated. {CONCLUSIONS}: {G}raphs help understanding the progress of instantaneous incidence; however, tables of cumulative average incidence over decades should be preferred because of higher stability.}, keywords = {{FRANCE}}, booktitle = {}, journal = {{E}xpert {R}eview of {V}accines}, volume = {15}, numero = {7}, pages = {927--936}, ISSN = {1744-8395}, year = {2016}, DOI = {10.1080/14760584.2016.1183483}, URL = {https://www.documentation.ird.fr/hor/fdi:010067219}, }