@article{fdi:010066919, title = {{M}olecular characterization of {O}rf virus in goats in {G}abon, {C}entral {A}frica}, author = {{M}aganga, {G}. {D}. and {R}elmy, {A}. and {B}akkali-{K}assimi, {L}. and {N}goubangoye, {B}. and {T}soumbou, {T}. and {B}ouchier, {C}. and {N}'{D}ilimabaka, {N}. and {L}eroy, {E}ric and {Z}ientara, {S}. and {B}erthet, {N}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {O}rf or contagious ecthyma is a zoonotic viral infection with a potential serious health threat for the small ruminants industry as well as humans. {I}t is currently emerging in new territories. {R}esults: {E}ight suspected clinical cases of pustular dermatitis in goats occurred in the rural area of {T}ebe, in southeastern {G}abon, in {J}anuary 2013. {T}he orf virus ({ORFV}) was detected by high-throughput sequencing on sera, buccal swabs and scab pool samples. {I}t was confirmed in six out of eight sick goats by using specific {PCR} targeting the major envelope protein ({B}2{L}) and the orf virus interferon resistance ({VIR}) genes. {P}hylogenetic analysis revealed that the {G}abonese strain and {S}outh {K}orean strains evolved from a common ancestor, suggesting an {A}sian origin of the {ORFV}' {G}abonese strain. {C}onclusions: {T}his study provides the molecular detection of the {ORFV} strain involved in the cases of pustular dermatitis in goats and highlights its circulation in {G}abon.}, keywords = {{O}rf virus ; {G}oats ; {H}igh-throughput sequencing ; {PCR} ; {GABON}}, booktitle = {}, journal = {{V}irology {J}ournal}, volume = {13}, numero = {}, pages = {art. 79 [5 p.]}, ISSN = {1743-422{X}}, year = {2016}, DOI = {10.1186/s12985-016-0535-1}, URL = {https://www.documentation.ird.fr/hor/fdi:010066919}, }