%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Wieringa, Franck
%A Sophonneary, P.
%A Whitney, S.
%A Mao, B.
%A Berger, Jacques
%A Conkle, J.
%A Dijkhuizen, M. A.
%A Laillou, A.
%T Low prevalence of iron and vitamin A deficiency among Cambodian women of reproductive age
%D 2016
%L fdi:010066891
%G ENG
%J Nutrients
%@ 2072-6643
%K iron ; vitamin A ; deficiency ; Cambodia ; women of reproductive age ; inflammation
%K CAMBODGE
%M ISI:000374590200020
%N 4
%P art. 197 [8 ]
%R 10.3390/nu8040197
%U https://www.documentation.ird.fr/hor/fdi:010066891
%> https://www.documentation.ird.fr/intranet/publi/2016/06/010066891.pdf
%V 8
%W Horizon (IRD)
%X Nearly half of women of reproductive age (WRA) in Cambodia are anemic. To guide interventions, national data on nutritional causes of anemia, including iron deficiency and vitamin A deficiency, are needed. In 2012, a national household survey in WRA on antibodies to routine vaccine-preventable disease immunity was performed. We used serum samples from this survey to estimate the prevalence of iron and vitamin A deficiency in 2112 Cambodian WRA, aged 15 to 39 years. Iron deficiency was classified as low or marginal iron stores (ferritin concentrations corrected for inflammation <15 mu g/L and <50 mu g/L respectively; Fer), iron deficient erythropoiesis (soluble transferrin receptor concentrations >8.3 mg/L; sTfR), or low total body iron (TBI) derived from Fer and sTfR concentrations (<0 mg/kg). Vitamin A status was classified using retinol binding protein (RBP) concentrations corrected for inflammation as deficient (<0.70 mu mol/L) or marginal (<1.05 mu mol/L. Overall, the prevalence of low iron stores, low TBI and iron deficient erythropoiesis was 8.1%, 5.0% and 9.3% respectively. Almost 40% of the women had marginal iron stores. Iron status was better in women living in urban areas compared to rural areas (p < 0.05 for TBI and sTfR). The prevalence of vitamin A deficiency was < 1%. These findings suggest that the contribution of iron and vitamin A deficiency to the high prevalence of anemia in Cambodian WRA may be limited. The etiology of anemia in Cambodia needs to be elucidated further to guide current policies on anemia.
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