@article{fdi:010066853,
  title = {{E}ffects of larvicidal and larval nutritional stresses on {A}nopheles gambiae development, survival and competence for {P}lasmodium falciparum},
  author = {{V}antaux, {A}m{\'e}lie and {O}uattarra, {I}. and {L}ef{\`e}vre, {T}hierry and {D}abir{\'e}, {K}. {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {M}any studies have shown that the environment in which larvae develop can influence adult characteristics with consequences for the transmission of pathogens. {W}e investigated how two environmental stresses (larviciding and nutritional stress) interact to affect {A}nopheles gambiae (previously {A}n. gambiae {S} molecular form) life history traits and its susceptibility for field isolates of its natural malaria agent {P}lasmodium falciparum. {M}ethods: {L}arvae were reared in the presence or not of a sub-lethal concentration of larvicide and under a high and low food regimen. {D}evelopment time, individual size, adult survival and competence for {P}. falciparum were assessed. {R}esults: {I}ndividuals under low food regimen took more time to develop, had a lower development success and were smaller while there was no main effect of larvicide exposure on these traits. {H}owever, larvicide exposure impacted individual size in interaction with nutritional stress. {F}emale survival was affected by the interaction between gametocytemia, parasite exposure and larval diet, as well as the interaction between gametocytemia, parasite exposure and larvicidal stress, and the interaction between gametocytemia, larvicidal exposure and larval diet. {A}mong the 951 females dissected 7 days post-infection, 559 (58.78 %) harboured parasites. {P}arasite prevalence was significantly affected by the interaction between larvicidal stress and larval diet. {I}ndeed, females under low food regimen had a higher prevalence than females under high food regimen and this difference was greater under larvicidal stress. {T}he two stresses did not impact parasite intensity. {C}onclusions: {W}e found that larval nutritional and larvicidal stresses affect mosquito life history traits in complex ways, which could greatly affect {P}. falciparum transmission. {F}urther studies combining field-based trials on larvicide use and mosquito experimental infections would give a more accurate understanding of the effects of this vector control tool on malaria transmission.},
  keywords = {{B}ti ; {L}arvicide ; {L}arval diet ; {S}tress ; {M}osquito competence ; {M}alaria parasite ; {P}lasmodium falciparum ; {BURKINA} {FASO}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {9},
  numero = {},
  pages = {art. 226 [11 p.]},
  ISSN = {1756-3305},
  year = {2016},
  DOI = {10.1186/s13071-016-1514-5},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066853},
}