@article{fdi:010066844,
  title = {{G}enomic and physiological analysis reveals versatile metabolic capacity of deep-sea {P}hotobacterium phosphoreum {ANT}-2200},
  author = {{Z}hang, {S}. {D}. and {S}antini, {C}. {L}. and {Z}hang, {W}. {J}. and {B}arbe, {V}. and {M}angenot, {S}. and {G}uyomar, {C}. and {G}arel, {M}. and {C}hen, {H}. {T}. and {L}i, {X}. {G}. and {Y}in, {Q}. {J}. and {Z}hao, {Y}. and {A}rmengaud, {J}. and {G}aillard, {J}. {C}. and {M}artini, {S}{\'e}verine and {P}radel, {N}athalie and {V}idaud, {C}. and {A}lberto, {F}. and {M}edigue, {C}. and {T}amburini, {C}. and {W}u, {L}. {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}acteria of the genus {P}hotobacterium thrive worldwide in oceans and show substantial eco-physiological diversity including free-living, symbiotic and piezophilic life styles. {G}enomic characteristics underlying this variability across species are poorly understood. {H}ere we carried out genomic and physiological analysis of {P}hotobacterium phosphoreum strain {ANT}-2200, the first deep-sea luminous bacterium of which the genome has been sequenced. {U}sing optical mapping we updated the genomic data and reassembled it into two chromosomes and a large plasmid. {G}enomic analysis revealed a versatile energy metabolic potential and physiological analysis confirmed its growth capacity by deriving energy from fermentation of glucose or maltose, by respiration with formate as electron donor and trimethlyamine {N}-oxide ({TMAO}), nitrate or fumarate as electron acceptors, or by chemo-organo-heterotrophic growth in rich media. {D}espite that it was isolated at a site with saturated dissolved oxygen, the {ANT}-2200 strain possesses four gene clusters coding for typical anaerobic enzymes, the {TMAO} reductases. {E}levated hydrostatic pressure enhances the {TMAO} reductase activity, mainly due to the increase of isoenzyme {T}or{A}1. {T}he high copy number of the {TMAO} reductase isoenzymes and pressure-enhanced activity might imply a strategy developed by bacteria to adapt to deep-sea habitats where the instant {TMAO} availability may increase with depth.},
  keywords = {{D}eep-sea adaptation ; {B}ioluminescence ; {TMAO} reductase ; {H}ydrostatic pressure ; {A}naerobic respiration},
  booktitle = {},
  journal = {{E}xtremophiles},
  volume = {20},
  numero = {3},
  pages = {301--310},
  ISSN = {1431-0651},
  year = {2016},
  DOI = {10.1007/s00792-016-0822-1},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066844},
}