@article{fdi:010066763, title = {{POCIS} passive samplers as a monitoring tool for pharmaceutical residues and their transformation products in marine environment}, author = {{B}ueno, {M}. {J}. {M}. and {H}errera, {S}. and {M}unaron, {D}. and {B}oillot, {C}. and {F}enet, {H}. and {C}hiron, {S}erge and {G}omez, {E}.}, editor = {}, language = {{ENG}}, abstract = {{I}n the last years, several scientific studies have shown that carbamazepine ({CBZ}) is one of the most frequently detected pharmaceutical in aquatic environment. {H}owever, little data is available on its detection and its transformation products ({TP}s) in marine water. {T}he use of polar organic chemical integrative sampling ({POCIS}) passive samplers as a semi-quantitative and qualitative tool for screening of pharmaceuticals and {TP}s in seawater has been studied. {F}urthermore, the uptake rates of the target compounds were also determined under laboratory experiments to characterize the levels accumulated in devices. {T}he results confirmed the presence of residues of anticonvulsant {CBZ} as well as some of its main metabolites, over a 1-year monitoring campaign carried out in {F}rench coast on the {M}editerranean {S}ea. {T}he work reports for the first time the presence of two {TP}s (10,11-dihydro-10,11-trans-dihydroxycarbamazepine ({TRANS}) and 10-hydroxy-10,11-dihydrocarbamazepine (10{OH})) in marine water. {T}he results contribute in assessing the environmental and human health risk of pharmaceuticals on coastal areas.}, keywords = {{POCIS} ; {E}merging contaminants ; {M}etabolites ; {S}creening ; {M}editerranean {S}ea ; {C}arbamazepine ; {MEDITERRANEE}}, booktitle = {}, journal = {{E}nvironmental {S}cience and {P}ollution {R}esearch}, volume = {23}, numero = {6}, pages = {5019--5029}, ISSN = {0944-1344}, year = {2016}, DOI = {10.1007/s11356-014-3796-5}, URL = {https://www.documentation.ird.fr/hor/fdi:010066763}, }