@article{fdi:010066744,
  title = {{G}enetic diversity and phylogeny of {A}edes aegypti, the main arbovirus vector in the {P}acific},
  author = {{C}alvez, {E}. and {G}uillaumot, {L}. and {M}illet, {L}aurent and {M}arie, {J}. and {B}ossin, {H}. and {R}ama, {V}. and {F}aamoe, {A}. and {K}ilama, {S}. and {T}eurlai, {M}. and {M}athieu-{D}aud{\'e}, {F}ran{\c{c}}oise and {D}upont-{R}ouzeyrol, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {T}he {P}acific region is an area unique in the world, composed of thousands of islands with differing climates and environments. {T}he spreading and establishment of the mosquito {A}edes aegypti in these islands might be linked to human migration. {A}e. aegypti is the major vector of arboviruses (dengue, chikungunya and {Z}ika viruses) in the region. {T}he intense circulation of these viruses in the {P}acific during the last decade led to an increase of vector control measures by local health authorities. {T}he aim of this study is to analyze the genetic relationships among {A}e. aegypti populations in this region. {M}ethodology/{P}rincipal {F}inding {W}e studied the genetic variability and population genetics of 270 {A}e. aegypti, sampled from 9 locations in {N}ew {C}aledonia, {F}iji, {T}onga and {F}rench {P}olynesia by analyzing nine microsatellites and two mitochondrial {DNA} regions ({CO}1 and {ND}4). {M}icrosatellite markers revealed heterogeneity in the genetic structure between the western, central and eastern {P}acific island countries. {T}he microsatellite markers indicate a statistically moderate differentiation ({FST} = 0.136; {P} < = 0.001) in relation to island isolation. {A} high degree of mixed ancestry can be observed in the most important towns (e.g. {N}oumea, {S}uva and {P}apeete) compared with the most isolated islands (e.g. {O}uvea and {V}aitahu). {P}hylogenetic analysis indicated that most of samples are related to {A}sian and {A}merican specimens. {C}onclusions/{S}ignificance {O}ur results suggest a link between human migrations in the {P}acific region and the origin of {A}e. aegypti populations. {T}he genetic pattern observed might be linked to the island isolation and to the different environmental conditions or ecosystems.},
  keywords = {{NOUVELLE} {CALEDONIE} ; {FIJI} ; {TONGA} ; {POLYNESIE} {FRANCAISE} ; {PACIFIQUE} {ILES}},
  booktitle = {},
  journal = {{P}los {N}eglected {T}ropical {D}iseases},
  volume = {10},
  numero = {1},
  pages = {e0004374 [17 p.]},
  ISSN = {1935-2735},
  year = {2016},
  DOI = {10.1371/journal.pntd.0004374},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066744},
}