Publications des scientifiques de l'IRD

Apaire-Marchais V., Ogliastro M., Chandre Fabrice, Pennetier Cédric, Raymond V., Lapied B. (2016). Virus and calcium : an unexpected tandem to optimize insecticide efficacy. Environmental Microbiology Reports, 8 (2), p. 168-178. ISSN 1758-2229.

Titre du document
Virus and calcium : an unexpected tandem to optimize insecticide efficacy
Année de publication
2016
Type de document
Article référencé dans le Web of Science WOS:000372931000001
Auteurs
Apaire-Marchais V., Ogliastro M., Chandre Fabrice, Pennetier Cédric, Raymond V., Lapied B.
Source
Environmental Microbiology Reports, 2016, 8 (2), p. 168-178 ISSN 1758-2229
The effective control of insect pests is based on the rational use of the most efficient and safe insecticide treatments. To increase the effects of classical insecticides and to avoid the ability of certain pest insects to develop resistance, it is essential to propose novel strategies. Previous studies have shown that calcium-dependent phosphorylation/dephosphorylation is now considered as a new cellular mechanism for increasing the target sensitivity to insecticides. Because it is known that virus entry is correlated with intracellular calcium concentration rise, this report attempts to present the most important data relevant to the feasibility of combining an insect virus such as baculovirus or densovirus with an insecticide. In this case, the insect virus is not used as a bioinsecticide but acts as a synergistic agent able to trigger calcium rise and to activate calcium-dependent intracellular signalling pathways involved in the increase of the membrane receptors and/or ion channels sensitivity to insecticides. This virus-insecticide mixture represents a promising alternative to optimize the efficacy of insecticides against insect pests while reducing the doses.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Entomologie médicale / Parasitologie / Virologie [052]
Localisation
Fonds IRD [F B010066728]
Identifiant IRD
fdi:010066728
Contact