@article{fdi:010066665,
  title = {{S}tudy of {L}eishmania pathogenesis in mice : experimental considerations},
  author = {{L}oeuillet, {C}. and {B}anuls, {A}nne-{L}aure and {H}ide, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}lthough leishmaniases are endemic in 98 countries, they are still considered neglected tropical diseases. {L}eishmaniases are characterized by the emergence of new virulent and asymptomatic strains of {L}eishmania spp. and, as a consequence, by a very diverse clinical spectrum. {T}o fight more efficiently these parasites, the mechanisms of host defense and of parasite virulence need to be thoroughly investigated. {T}o this aim, animal models are widely used. {H}owever, the results obtained with these models are influenced by several experimental parameters, such as the mouse genetic background, parasite genotype, inoculation route/infection site, parasite dose and phlebotome saliva. {I}n this review, we propose an update on their influence in the two main clinical forms of the disease: cutaneous and visceral leishmaniases.},
  keywords = {{L}eishmaniases ; {V}isceral ; {C}utaneous ; {M}ice ; {D}ose ; {I}noculation site ; {S}aliva},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {9},
  numero = {},
  pages = {art. 144 [12 p.]},
  ISSN = {1756-3305},
  year = {2016},
  DOI = {10.1186/s13071-016-1413-9},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066665},
}